ID   RSE1_YARLI              Reviewed;        1143 AA.
AC   Q6CAH5;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Pre-mRNA-splicing factor RSE1;
GN   Name=RSE1; OrderedLocusNames=YALI0D02717g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RSE1 family. {ECO:0000305}.
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DR   EMBL; CR382130; CAG80525.1; -; Genomic_DNA.
DR   RefSeq; XP_502337.1; XM_502337.1.
DR   AlphaFoldDB; Q6CAH5; -.
DR   SMR; Q6CAH5; -.
DR   STRING; 4952.CAG80525; -.
DR   EnsemblFungi; CAG80525; CAG80525; YALI0_D02717g.
DR   GeneID; 2910539; -.
DR   KEGG; yli:YALI0D02717g; -.
DR   VEuPathDB; FungiDB:YALI0_D02717g; -.
DR   HOGENOM; CLU_003246_0_0_1; -.
DR   InParanoid; Q6CAH5; -.
DR   OMA; FFLVQTE; -.
DR   Proteomes; UP000001300; Chromosome D.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..1143
FT                   /note="Pre-mRNA-splicing factor RSE1"
FT                   /id="PRO_0000218637"
SQ   SEQUENCE   1143 AA;  121857 MW;  265E86C6A013AC82 CRC64;
     MHNTNLKYFT SPLNSTTLAS SAMLYHSTLR SSSPKSAICG RFSGKSQQVI TLSSTGNALY
     LYSHDGDTGT VTLIHTHLTH CQVREIRAFR LPGLKKDYVI ASSDSGVISV LEFRHNRFVS
     LHKEAYGRSG IRRVVPGEFL AVDPKGRACM LASVEKSKLV YVLNRQGADI VISSPLEAHT
     SCVTYFVVAC DVAYENPVFA AIETPVGETS PGKQLVFYEL DLGLNHVIRK APVDIPNSTS
     HVTAVPGGTD GPGGVLVFST NAIVHHVAGA AGGASTGAAG STKIALPKPA AGYDNVIVAS
     ALHQSRDLFF YIAQNTRGDL FKISRDSETQ HWSVLYFGTM SCVCTSLTIL KSAHMVCLSE
     QGDSHMMFFE SLGDDDAPEN VYDVISPSPY LTVTQTLFEL KPVFDSVVGV NTTSSDHVGP
     VPNVLSLISA TRGGLKLISH ALKPSIIVAS PLPEPPSKLW TMRDGAGSDK YIVLSYANAT
     LVLEIGDSVV ETTSSGLTLD KPTLHCGSVG SSYVQVMTDG MNVIPMSREG SSESLPATKW
     TAPSGQVICA SSSSHQVVLG LTSSLFYFED TPGSELSAYD GAYELSSPPT AVAVAPVPAG
     RVRSPFVAVA TDDETVRIVS VDPESMFETV AVQGLMATAS SLALLSVGQV LYLHMGLANG
     VYVRVELDPL TGEIVGSWSK FVGLGRLSVV PVTCGGEESI LVSSRGVKTC LGHVNATSDT
     WVPTGGNSAP FFALDAISGE PLDLAHSFHT QDCPHGVIGV AGSTLKIFTV NTAQKWTENE
     VKLEGTAKRL IQHDATTLTI TQNPDRLVSV DNGAVGITKD LGGPPTSICE VMFGDGKRYF
     AVGGSRDGSP GTSGTSGYIS IFSSSSLGHV HTTEVEAPPL ALCAYNGLLV AGIGSQVRLY
     ALGLKQVLRK AQIELSKRVT CLAHFAGSNR VAVGDIRQSV TVCVVLEEDS GHVIYPLVCD
     KISRQVTCLF FVDYETVALG DRFGGFTMLR IPSEASKLAD EDHNAVHLRQ LEPTLNGPAH
     FRFDHVASFH IEDVPVAIHM YNDYLVVCGL LGTVSAFVPV VSPKQSRDLK TIEKFVCASD
     PGLMGRDHGR FRGYYVPVKE VVDGDMLREV LVMDEKRREE VGEKTGLGVE GAVGRVVNVM
     KCV