ID   RSFA_BACSU              Reviewed;         258 AA.
AC   P39650;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Prespore-specific transcriptional regulator RsfA;
GN   Name=rsfA; Synonyms=ywfN; OrderedLocusNames=BSU37620; ORFNames=ipa-92r;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7934828; DOI=10.1111/j.1365-2958.1993.tb01963.x;
RA   Glaser P., Kunst F., Arnaud M., Coudart M.P., Gonzales W., Hullo M.-F.,
RA   Ionescu M., Lubochinsky B., Marcelino L., Moszer I., Presecan E.,
RA   Santana M., Schneider E., Schweizer J., Vertes A., Rapoport G., Danchin A.;
RT   "Bacillus subtilis genome project: cloning and sequencing of the 97 kb
RT   region from 325 degrees to 333 degrees.";
RL   Mol. Microbiol. 10:371-384(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   CHARACTERIZATION.
RC   STRAIN=168;
RX   PubMed=10629188; DOI=10.1128/jb.182.2.418-424.2000;
RA   Wu L.J., Errington J.;
RT   "Identification and characterization of a new prespore-specific regulatory
RT   gene, rsfA, of Bacillus subtilis.";
RL   J. Bacteriol. 182:418-424(2000).
CC   -!- FUNCTION: Seems to improve the efficiency of sporulation by fine-tuning
CC       the expression of genes in the sigma F regulon, particularly the timing
CC       of their expression. Negatively regulates spoIIR and its own synthesis.
CC   -!- SUBCELLULAR LOCATION: Forespore. Note=Expressed in the forespore.
CC       Colocalizes with DNA.
CC   -!- DEVELOPMENTAL STAGE: Expressed during sporulation.
CC   -!- INDUCTION: Expression is sigma F and sigma G-dependent.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X73124; CAA51648.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15789.1; -; Genomic_DNA.
DR   PIR; S39747; S39747.
DR   RefSeq; NP_391642.1; NC_000964.3.
DR   RefSeq; WP_003243464.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; P39650; -.
DR   SMR; P39650; -.
DR   IntAct; P39650; 1.
DR   STRING; 224308.BSU37620; -.
DR   PaxDb; P39650; -.
DR   PRIDE; P39650; -.
DR   EnsemblBacteria; CAB15789; CAB15789; BSU_37620.
DR   GeneID; 937126; -.
DR   KEGG; bsu:BSU37620; -.
DR   PATRIC; fig|224308.179.peg.4074; -.
DR   eggNOG; ENOG5030SGP; Bacteria.
DR   InParanoid; P39650; -.
DR   OMA; KQRQDAW; -.
DR   BioCyc; BSUB:BSU37620-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0042763; C:intracellular immature spore; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR014243; DNA_bind_RsfA.
DR   InterPro; IPR001005; SANT/Myb.
DR   PANTHER; PTHR41302; PTHR41302; 1.
DR   TIGRFAMs; TIGR02894; DNA_bind_RsfA; 1.
DR   PROSITE; PS50090; MYB_LIKE; 1.
PE   1: Evidence at protein level;
KW   Activator; DNA-binding; Reference proteome; Repressor; Sporulation;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..258
FT                   /note="Prespore-specific transcriptional regulator RsfA"
FT                   /id="PRO_0000097484"
FT   DOMAIN          1..57
FT                   /note="Myb-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT   REGION          238..258
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   258 AA;  29728 MW;  67C65A0483BF8B5C CRC64;
     MTKQRQDAWS EENDLLLAET VLRHVREGST QLNAFEEVGD KLNRTSAACG FRWNAVVRHQ
     YEKALQLAKK QRKQRMRALG NGQPAKKRLL YQPPAVDPEI IQETAAEEPV KTETPSVENE
     QPLMSGEHMP FVDESFKEEL ASLSHLLSPQ TPAAAPEMTM NDVIRFLQNY EGNHEQSSAL
     KMENERLKKE NQELQNKTEQ LEAEVQKLEK DQKTIQEDYE TLVKIMNRAR KLVLFEEDEH
     ASPSFKMDRN GNLEKLAE