ID   BC1_TGMVY               Reviewed;         293 AA.
AC   P03566;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 2.
DT   23-FEB-2022, entry version 78.
DE   RecName: Full=Movement protein BC1;
DE   AltName: Full=Movement protein BL1;
GN   ORFNames=BC1, BL1;
OS   Tomato golden mosaic virus (strain Yellow vein) (TGMV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=223341;
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   von Arnim A.G., Stanley J.;
RT   "Symptom determinants of tomato golden mosaic virus are encoded on DNA B.";
RL   Submitted (JUL-1991) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16453557; DOI=10.1002/j.1460-2075.1984.tb02114.x;
RA   Hamilton W.D.O., Stein V.E., Coutts R.H.A., Buck K.W.;
RT   "Complete nucleotide sequence of the infectious cloned DNA components of
RT   tomato golden mosaic virus: potential coding regions and regulatory
RT   sequences.";
RL   EMBO J. 3:2197-2205(1984).
CC   -!- FUNCTION: Movement protein involved in the cell-to-cell and systemic
CC       transport of viral genomic DNA. Begomoviruses use 2 proteins to
CC       transport their DNA from cell to cell. The nuclear shuttle protein
CC       (NSP) shuttles it between nucleus and cytoplasm and the movement
CC       protein (MP) probably transports the DNA-NSP complex to the cell
CC       periphery and facilitates further movement across the cell wall (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Binds to dimeric supercoiled plasmid DNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell membrane {ECO:0000250}; Peripheral
CC       membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host
CC       microsome membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host endoplasmic
CC       reticulum membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Found on ER-derived
CC       vesicles. {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the begomovirus movement protein BC1 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=K02030; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; M73794; AAA46584.1; -; Genomic_DNA.
DR   EMBL; K02030; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; A04169; QQCVLG.
DR   Proteomes; UP000007405; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR000211; Gemini_BL.
DR   Pfam; PF00845; Gemini_BL1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Host cell membrane; Host endoplasmic reticulum; Host membrane;
KW   Host microsome; Membrane; Phosphoprotein; Reference proteome; Transport;
KW   Viral movement protein.
FT   CHAIN           1..293
FT                   /note="Movement protein BC1"
FT                   /id="PRO_0000222258"
FT   REGION          207..228
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        11
FT                   /note="V -> A (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   293 AA;  32933 MW;  E024E3F285C89012 CRC64;
     MDSQLACPPN VFNYIESNRD EYQLSHDLTE IILQFPSTAS QLSARLSRSC MKIDHCVIEF
     RQQVPINATG SVVVEIHDKR MTDNESLQAS WTFPVRCNID LHYFSSSFFS LKDPIPWKLY
     YKVCDSNVHQ RTHFAKFKGK LKLSTAKHSV DIPFRAPTVK ILSKQFTDKD VDFSHVGYGK
     WDRKMIRSAS TSTIGLTGPI ELRPGESWAS RSTIGPSPSY AGSDQGDAMH PYKHLNRLGT
     TILDPGESAS IIGAERTQSN ITMSMVQLNE IVRATVQECI NTNCTPSQPK TLQ