BC1_TMOV
ID BC1_TMOV Reviewed; 293 AA.
AC Q06660;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 2.
DT 23-FEB-2022, entry version 69.
DE RecName: Full=Movement protein BC1;
DE AltName: Full=Movement protein BL1;
GN ORFNames=BC1, BL1;
OS Tomato mottle virus (isolate Florida) (ToMoV).
OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC Geplafuvirales; Geminiviridae; Begomovirus.
OX NCBI_TaxID=223359;
OH NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1469361; DOI=10.1099/0022-1317-73-12-3225;
RA Abouzid A.M., Polston J.E., Hiebert E.;
RT "The nucleotide sequence of tomato mottle virus, a new geminivirus isolated
RT from tomatoes in Florida.";
RL J. Gen. Virol. 73:3225-3229(1992).
RN [2]
RP SEQUENCE REVISION.
RA Hiebert E.;
RL Submitted (APR-1993) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Movement protein involved in the cell-to-cell and systemic
CC transport of viral genomic DNA. Begomoviruses use 2 proteins to
CC transport their DNA from cell to cell. The nuclear shuttle protein
CC (NSP) shuttles it between nucleus and cytoplasm and the movement
CC protein (MP) probably transports the DNA-NSP complex to the cell
CC periphery and facilitates further movement across the cell wall (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Binds to dimeric supercoiled plasmid DNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host cell membrane {ECO:0000250}; Peripheral
CC membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host
CC microsome membrane {ECO:0000250}; Peripheral membrane protein
CC {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host endoplasmic
CC reticulum membrane {ECO:0000250}; Peripheral membrane protein
CC {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Found on ER-derived
CC vesicles. {ECO:0000250}.
CC -!- PTM: Phosphorylated. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the begomovirus movement protein BC1 family.
CC {ECO:0000305}.
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DR EMBL; L14461; AAC32419.1; -; Genomic_DNA.
DR PIR; JQ1874; JQ1874.
DR RefSeq; NP_047254.1; NC_001939.1.
DR GeneID; 956414; -.
DR KEGG; vg:956414; -.
DR Proteomes; UP000008249; Genome.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR000211; Gemini_BL.
DR Pfam; PF00845; Gemini_BL1; 1.
PE 3: Inferred from homology;
KW DNA-binding; Host cell membrane; Host endoplasmic reticulum; Host membrane;
KW Host microsome; Membrane; Phosphoprotein; Reference proteome; Transport;
KW Viral movement protein.
FT CHAIN 1..293
FT /note="Movement protein BC1"
FT /id="PRO_0000222259"
SQ SEQUENCE 293 AA; 33265 MW; 571F2AA3D1F5648A CRC64;
MDSQLVNPPS AFNYIESHRD EYQLSHDLTE IILQFPSTAS QLTARLSRSC MKIDHCVIEY
RQQVPINATG SVIVEIHDKR MTENESLQAS WTFPIRCNID LHYFSASFFS LKDPIPWKLY
YRVCDTNVHQ RTHFAKFKGK LKLSTAKHSV DIPFRAPTVK ILSKQFTDKD VDFSHVDYGK
WERKPIRCAS MSRLGLRGPI EIRPGESWAS RSTIGIGHSD ADSEVENELH PYRHLNRLGT
GILDPGESAS IVGAQKAESN ITMSMGQLNE LIRTTVHECI NSNCKASQTK SLK