ID   RSH6A_XENTR             Reviewed;         526 AA.
AC   A1L0Z6; Q28D10;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Radial spoke head protein 6 homolog A;
DE   AltName: Full=Radial spoke head-like protein 1;
GN   Name=rsph6a; Synonyms=rshl1; ORFNames=TGas107g21.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Oviduct;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC       {ECO:0000250|UniProtKB:Q8CDR2}. Cytoplasm, cytoskeleton, flagellum
CC       axoneme {ECO:0000250|UniProtKB:Q8CDR2}.
CC   -!- SIMILARITY: Belongs to the flagellar radial spoke RSP4/6 family.
CC       {ECO:0000305}.
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DR   EMBL; CR855771; CAJ83446.1; -; mRNA.
DR   EMBL; BC127351; AAI27352.1; -; mRNA.
DR   RefSeq; NP_001016760.1; NM_001016760.2.
DR   AlphaFoldDB; A1L0Z6; -.
DR   SMR; A1L0Z6; -.
DR   PaxDb; A1L0Z6; -.
DR   DNASU; 549514; -.
DR   GeneID; 549514; -.
DR   KEGG; xtr:549514; -.
DR   CTD; 81492; -.
DR   Xenbase; XB-GENE-1014690; rsph6a.
DR   eggNOG; ENOG502QSU4; Eukaryota.
DR   InParanoid; A1L0Z6; -.
DR   OMA; HGPYMRD; -.
DR   OrthoDB; 619686at2759; -.
DR   TreeFam; TF324531; -.
DR   Proteomes; UP000008143; Chromosome 8.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0001534; C:radial spoke; IEA:InterPro.
DR   GO; GO:0035082; P:axoneme assembly; IBA:GO_Central.
DR   GO; GO:0003341; P:cilium movement; IBA:GO_Central.
DR   GO; GO:0060294; P:cilium movement involved in cell motility; IEA:InterPro.
DR   InterPro; IPR006802; Radial_spoke.
DR   PANTHER; PTHR13159; PTHR13159; 1.
DR   Pfam; PF04712; Radial_spoke; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Cytoplasm; Cytoskeleton; Flagellum;
KW   Reference proteome.
FT   CHAIN           1..526
FT                   /note="Radial spoke head protein 6 homolog A"
FT                   /id="PRO_0000312762"
FT   REGION          180..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          371..411
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          469..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        180..211
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..395
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..507
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        508..526
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        501
FT                   /note="A -> V (in Ref. 1; CAJ83446)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        524
FT                   /note="Missing (in Ref. 1; CAJ83446)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   526 AA;  58497 MW;  E69BD7B695A67CB5 CRC64;
     MTDNAIPGPL DPEELQIQYA KSFLLQTDNS GLSLYEHLSA LLSRILSERP PNALEVFESL
     SAELHWSRLK QGSDVLRAPR EESHTCRKAE VQRALFSRGD GEGEESEAEG EMTESPLPNL
     LDLAHLLQQG GVNLGRDEAV RISLALKRLT DTHPLQVCHF WGKILGSGGS YLVAEVQFRE
     GEDDEAEEGG EEEEKGEVED DVEEEENEEA EDLPPKSTYR PPPVIPKEEN GTGANKHVYY
     VCSEAGAEWV RLPPVTPAQI SAARKIRHLF TGNLDAPVIT YPPFPGTEIN LLRAQIARIS
     AGTHVSPLGY YQFGEEEGEE EEEGAVRDTY EENPDFEGIP VSELVESLSN WVHHVQHILP
     QGRCVWVNTS VKSEEEEDEE EAEEEEKEEE NEPEPEVGPP LLTPLSEDAE IGQTPPWTAF
     LSTHLIPHYA LAVLRSNLWP GAYTVSSAKK FENIYIGWGL KYMPEGYSPP APPAPQAEYP
     SGPEITESTD PTVEEEQALK AAKEEAEAAA EEMEEEEDEE EEEEDD