RSL1_ARATH
ID RSL1_ARATH Reviewed; 307 AA.
AC Q9FJ00;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Putative transcription factor bHLH086 {ECO:0000305};
DE AltName: Full=Basic helix-loop-helix protein 86 {ECO:0000303|PubMed:12679534};
DE Short=AtbHLH86 {ECO:0000303|PubMed:12679534};
DE Short=bHLH 86 {ECO:0000303|PubMed:12679534};
DE AltName: Full=Protein ROOT HAIR DEFECTIVE 6-LIKE 1 {ECO:0000303|PubMed:17556585};
DE Short=AtRSL1 {ECO:0000303|PubMed:17556585};
DE Short=Protein RHD SIX-LIKE 1 {ECO:0000303|PubMed:17556585};
DE AltName: Full=Transcription factor EN 113 {ECO:0000305};
DE AltName: Full=bHLH transcription factor bHLH086 {ECO:0000303|PubMed:12679534};
GN Name=RSL1 {ECO:0000303|PubMed:17556585};
GN Synonyms=BHLH86 {ECO:0000303|PubMed:12679534}, EN113 {ECO:0000305};
GN OrderedLocusNames=At5g37800 {ECO:0000312|Araport:AT5G37800};
GN ORFNames=K22F20.8 {ECO:0000312|EMBL:BAB10359.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9872454; DOI=10.1093/dnares/5.5.297;
RA Nakamura Y., Sato S., Asamizu E., Kaneko T., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VII. Sequence
RT features of the regions of 1,013,767 bp covered by sixteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:297-308(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=17556585; DOI=10.1126/science.1142618;
RA Menand B., Yi K., Jouannic S., Hoffmann L., Ryan E., Linstead P.,
RA Schaefer D.G., Dolan L.;
RT "An ancient mechanism controls the development of cells with a rooting
RT function in land plants.";
RL Science 316:1477-1480(2007).
RN [7]
RP FUNCTION, INTERACTION WITH RHD6; TIFY10B/JAZ2; TIFY6A/JAZ4; TIFY5A/JAZ8;
RP TIFY7/JAZ9 AND TIFY9/JAZ10, SUBCELLULAR LOCATION, AND INDUCTION BY
RP JASMONATE.
RX PubMed=31988260; DOI=10.1105/tpc.19.00617;
RA Han X., Zhang M., Yang M., Hu Y.;
RT "Arabidopsis JAZ proteins interact with and suppress RHD6 transcription
RT factor to regulate jasmonate-stimulated root hair development.";
RL Plant Cell 32:1049-1062(2020).
CC -!- FUNCTION: Transcription factor that is specifically required for the
CC development of root hairs (PubMed:17556585). Acts with RHD6 to
CC positively regulate root hair development (PubMed:17556585). Acts
CC downstream of genes that regulate epidermal pattern formation, such as
CC GL2 (PubMed:17556585). Acts with RHD6 as transcription factor that
CC integrates a jasmonate (JA) signaling pathway that stimulates root hair
CC growth (PubMed:31988260). {ECO:0000269|PubMed:17556585,
CC ECO:0000269|PubMed:31988260}.
CC -!- SUBUNIT: Homodimer (Probable). Forms heterodimers with RHD6
CC (PubMed:31988260). Interacts with TIFY10B/JAZ2, TIFY6A/JAZ4,
CC TIFY5A/JAZ8, TIFY7/JAZ9 and TIFY9/JAZ10 (PubMed:31988260).
CC {ECO:0000269|PubMed:31988260, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981,
CC ECO:0000269|PubMed:17556585, ECO:0000269|PubMed:31988260}.
CC -!- INDUCTION: Induced by jasmonate (JA) treatment.
CC {ECO:0000269|PubMed:31988260}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growht
CC conditions, but the double mutant seedlings rhd6-3 and rsl1-1 do not
CC develop root hairs. {ECO:0000269|PubMed:17556585}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10359.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB016873; BAB10359.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED94234.1; -; Genomic_DNA.
DR RefSeq; NP_198596.1; NM_123139.2.
DR AlphaFoldDB; Q9FJ00; -.
DR SMR; Q9FJ00; -.
DR BioGRID; 19009; 7.
DR IntAct; Q9FJ00; 4.
DR STRING; 3702.AT5G37800.1; -.
DR PaxDb; Q9FJ00; -.
DR PRIDE; Q9FJ00; -.
DR EnsemblPlants; AT5G37800.1; AT5G37800.1; AT5G37800.
DR GeneID; 833758; -.
DR Gramene; AT5G37800.1; AT5G37800.1; AT5G37800.
DR KEGG; ath:AT5G37800; -.
DR Araport; AT5G37800; -.
DR TAIR; locus:2156015; AT5G37800.
DR eggNOG; ENOG502QT4N; Eukaryota.
DR HOGENOM; CLU_072935_0_0_1; -.
DR InParanoid; Q9FJ00; -.
DR OMA; PATNHGN; -.
DR OrthoDB; 1411594at2759; -.
DR PhylomeDB; Q9FJ00; -.
DR PRO; PR:Q9FJ00; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FJ00; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0048766; P:root hair initiation; IGI:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..307
FT /note="Putative transcription factor bHLH086"
FT /id="PRO_0000358778"
FT DOMAIN 207..256
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..220
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 221..256
FT /note="Helix-loop-helix motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT COMPBIAS 180..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 307 AA; 33326 MW; 3C748F538A84BB8A CRC64;
MSLINEHCNE RNYISTPNSS EDLSSPQNCG LDEGASASSS STINSDHQNN QGFVFYPSGE
TIEDHNSLMD FNASSFFTFD NHRSLISPVT NGGAFPVVDG NMSYSYDGWS HHQVDSISPR
VIKTPNSFET TSSFGLTSNS MSKPATNHGN GDWLYSGSTI VNIGSRHEST SPKLAGNKRP
FTGENTQLSK KPSSGTNGKI KPKATTSPKD PQSLAAKNRR ERISERLKVL QELVPNGTKV
DLVTMLEKAI GYVKFLQVQV KVLAADEFWP AQGGKAPDIS QVKEAIDAIL SSSQRDSNST
RETSIAE
