ID   RSLBB_XENTR             Reviewed;         247 AA.
AC   Q5FVY2;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Ras-like protein family member 11B;
DE            EC=3.6.5.2 {ECO:0000250|UniProtKB:P01116};
GN   Name=rasl11b {ECO:0000312|EMBL:AAH89714.1};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1] {ECO:0000312|EMBL:AAH89714.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.2;
CC         Evidence={ECO:0000250|UniProtKB:P01116};
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Ras family.
CC       {ECO:0000255}.
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DR   EMBL; BC089714; AAH89714.1; -; mRNA.
DR   RefSeq; NP_001015774.1; NM_001015774.1.
DR   AlphaFoldDB; Q5FVY2; -.
DR   SMR; Q5FVY2; -.
DR   PaxDb; Q5FVY2; -.
DR   DNASU; 548491; -.
DR   Ensembl; ENSXETT00000025536; ENSXETP00000025536; ENSXETG00000011677.
DR   GeneID; 548491; -.
DR   KEGG; xtr:548491; -.
DR   CTD; 65997; -.
DR   Xenbase; XB-GENE-491056; rasl11b.
DR   eggNOG; KOG0395; Eukaryota.
DR   HOGENOM; CLU_041217_9_7_1; -.
DR   InParanoid; Q5FVY2; -.
DR   OMA; QVQIDGM; -.
DR   OrthoDB; 1384728at2759; -.
DR   PhylomeDB; Q5FVY2; -.
DR   TreeFam; TF318030; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000011677; Expressed in heart and 13 other tissues.
DR   ExpressionAtlas; Q5FVY2; baseline.
DR   GO; GO:0003925; F:G protein activity; IEA:UniProtKB-EC.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0048382; P:mesendoderm development; IEA:Ensembl.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51421; RAS; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..247
FT                   /note="Ras-like protein family member 11B"
FT                   /id="PRO_0000308370"
FT   REGION          29..247
FT                   /note="Small GTPase-like"
FT   REGION          205..228
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         40..47
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A58"
FT   BINDING         87..91
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A58"
FT   BINDING         152..155
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:Q96A58"
SQ   SEQUENCE   247 AA;  27550 MW;  FB3E03F4BBABE05F CRC64;
     MRLIQNMCTI TEYPPGTHTE CASSSAGTAS SRVIKIAVVG GSGVGKTALV VRFLTKRFIG
     DYERNAGNLY SRQVQIDGMN LAIQVQDTPG VQINDQNLDS NEQLNKSLRW ADAVVIVFSI
     TDCKSFDLIS RLHQHARQLH PDNRIPIVIV ANKADLLHLK QVEPQHGLQL ANMLGCTFYE
     VSVSENYIDV YNAFQVLCKE ISKQQNTGTP ERRKNSLIPR PKSPNMQDLK RRFKQALSAK
     VRTATSV