ID   BCCIP_DANRE             Reviewed;         301 AA.
AC   Q5BJJ7;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Protein BCCIP homolog;
GN   Name=bccip; ORFNames=zgc:110272;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: During interphase, required for microtubule organizing and
CC       anchoring activities. During mitosis, required for the organization and
CC       stabilization of the spindle pole. May promote cell cycle arrest and
CC       DNA repair. {ECO:0000250|UniProtKB:Q9P287}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9P287}.
CC       Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,
CC       centriole {ECO:0000250|UniProtKB:Q9P287}. Cytoplasm, cytoskeleton,
CC       spindle pole {ECO:0000250|UniProtKB:Q9P287}.
CC   -!- SIMILARITY: Belongs to the BCP1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC091454; AAH91454.1; -; mRNA.
DR   AlphaFoldDB; Q5BJJ7; -.
DR   SMR; Q5BJJ7; -.
DR   STRING; 7955.ENSDARP00000011145; -.
DR   PaxDb; Q5BJJ7; -.
DR   ZFIN; ZDB-GENE-050320-39; bccip.
DR   eggNOG; KOG3034; Eukaryota.
DR   InParanoid; Q5BJJ7; -.
DR   PhylomeDB; Q5BJJ7; -.
DR   PRO; PR:Q5BJJ7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005814; C:centriole; ISS:UniProtKB.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0097431; C:mitotic spindle pole; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0034453; P:microtubule anchoring; ISS:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0090307; P:mitotic spindle assembly; ISS:UniProtKB.
DR   GO; GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.
DR   InterPro; IPR025602; BCP1_family.
DR   PANTHER; PTHR13261; PTHR13261; 1.
DR   Pfam; PF13862; BCCIP; 1.
DR   PIRSF; PIRSF028983; BCP1; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cytoplasm; Cytoskeleton; DNA damage; DNA repair; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..301
FT                   /note="Protein BCCIP homolog"
FT                   /id="PRO_0000249689"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..43
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   301 AA;  33884 MW;  109AE0BC4016BBC0 CRC64;
     MASSAKRRAV ETGQNPQDSD ESSDEGLEDS GDDDSENSEE EVNEEVIVDF EAHTISDNDF
     HGIKTLLQQL FLKCHVNTSD LTDIIIQQNH IGSVIRQAEV PEDSDDEGDP DEVFGFISMV
     NLTERQGVEC LEKLKDMILD QCVKCSTPDG QERMENLLQG NAQSVGLLLS ERFVNVPPQI
     ALPLHKQLQK EMAEAQRTNK PSGKCQFCLM ISKTCKPLKK KSISAGDQAK DELLFVNDEE
     ECFYEQATVK FSYCVQDEAD SCATGKWSYD DEPMKPFRTV MVIPMDRMDT IMQKMTDYLT
     V