ID   BCCIP_DROME             Reviewed;         297 AA.
AC   Q9VFR0; Q8T9H9;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 2.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Protein BCCIP homolog;
GN   ORFNames=CG9286;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley; TISSUE=Ovary;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SIMILARITY: Belongs to the BCP1 family. {ECO:0000305}.
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DR   EMBL; AE014297; AAF54990.2; -; Genomic_DNA.
DR   EMBL; AY069286; AAL39431.1; -; mRNA.
DR   RefSeq; NP_650317.3; NM_142060.4.
DR   AlphaFoldDB; Q9VFR0; -.
DR   SMR; Q9VFR0; -.
DR   BioGRID; 66769; 3.
DR   IntAct; Q9VFR0; 4.
DR   STRING; 7227.FBpp0082298; -.
DR   PaxDb; Q9VFR0; -.
DR   PRIDE; Q9VFR0; -.
DR   EnsemblMetazoa; FBtr0082830; FBpp0082298; FBgn0038183.
DR   GeneID; 41690; -.
DR   KEGG; dme:Dmel_CG9286; -.
DR   UCSC; CG9286-RA; d. melanogaster.
DR   FlyBase; FBgn0038183; CG9286.
DR   VEuPathDB; VectorBase:FBgn0038183; -.
DR   eggNOG; KOG3034; Eukaryota.
DR   GeneTree; ENSGT00390000000696; -.
DR   HOGENOM; CLU_068770_1_1_1; -.
DR   InParanoid; Q9VFR0; -.
DR   OMA; MYTMLLE; -.
DR   OrthoDB; 1120393at2759; -.
DR   PhylomeDB; Q9VFR0; -.
DR   BioGRID-ORCS; 41690; 0 hits in 1 CRISPR screen.
DR   ChiTaRS; CG9286; fly.
DR   GenomeRNAi; 41690; -.
DR   PRO; PR:Q9VFR0; -.
DR   Proteomes; UP000000803; Chromosome 3R.
DR   Bgee; FBgn0038183; Expressed in larva and 28 other tissues.
DR   Genevisible; Q9VFR0; DM.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0019887; F:protein kinase regulator activity; ISS:FlyBase.
DR   GO; GO:0045859; P:regulation of protein kinase activity; ISS:FlyBase.
DR   InterPro; IPR025602; BCP1_family.
DR   PANTHER; PTHR13261; PTHR13261; 1.
DR   Pfam; PF13862; BCCIP; 1.
DR   PIRSF; PIRSF028983; BCP1; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..297
FT                   /note="Protein BCCIP homolog"
FT                   /id="PRO_0000249692"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        4
FT                   /note="N -> S (in Ref. 3; AAL39431)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        23
FT                   /note="S -> F (in Ref. 3; AAL39431)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        150
FT                   /note="P -> T (in Ref. 3; AAL39431)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        243
FT                   /note="K -> N (in Ref. 3; AAL39431)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   297 AA;  33429 MW;  A2C1AB4078271077 CRC64;
     MSANKQKKLS TMEVDPNEDV SSSSEDDDDD EPHPDAYKGN EEVQIDFEGR APVDPDAQGI
     SQLLQRLFLR AHINCNQMAD LIIAQNFIGS VICQCDDEGT ESETEDDNMV EDGTIFGITS
     VLNLTAKKDQ PSIAQLRTYI LDRAKTHASP EVQQQLKEIL DSEQRHVGFL INERFINIPA
     QISVPLLQSL QQEIEAAKAK KMKYDFGTLL LLVKFYRKES KKGKPGEDVY TNAEDELLSD
     RAKFSFEYSM ASETDSGMSG DWLEGDAVMT PYRKLLVLEA KKLPQLIDDI QRFINGE