位置:首页 > 蛋白库 > BCCIP_XENLA
BCCIP_XENLA
ID   BCCIP_XENLA             Reviewed;         308 AA.
AC   Q6GNI0;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Protein BCCIP homolog;
GN   Name=bccip;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: During interphase, required for microtubule organizing and
CC       anchoring activities. During mitosis, required for the organization and
CC       stabilization of the spindle pole. May promote cell cycle arrest and
CC       DNA repair. {ECO:0000250|UniProtKB:Q9P287}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9P287}.
CC       Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,
CC       centriole {ECO:0000250|UniProtKB:Q9P287}. Cytoplasm, cytoskeleton,
CC       spindle pole {ECO:0000250|UniProtKB:Q9P287}.
CC   -!- SIMILARITY: Belongs to the BCP1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC073531; AAH73531.1; -; mRNA.
DR   RefSeq; NP_001085917.1; NM_001092448.1.
DR   AlphaFoldDB; Q6GNI0; -.
DR   SMR; Q6GNI0; -.
DR   DNASU; 444344; -.
DR   GeneID; 444344; -.
DR   KEGG; xla:444344; -.
DR   CTD; 444344; -.
DR   Xenbase; XB-GENE-866129; bccip.L.
DR   OMA; DFEAYTI; -.
DR   OrthoDB; 1120393at2759; -.
DR   Proteomes; UP000186698; Chromosome 7L.
DR   Bgee; 444344; Expressed in pancreas and 19 other tissues.
DR   GO; GO:0005814; C:centriole; ISS:UniProtKB.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0097431; C:mitotic spindle pole; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0034453; P:microtubule anchoring; ISS:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0090307; P:mitotic spindle assembly; ISS:UniProtKB.
DR   GO; GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.
DR   InterPro; IPR025602; BCP1_family.
DR   PANTHER; PTHR13261; PTHR13261; 1.
DR   Pfam; PF13862; BCCIP; 1.
DR   PIRSF; PIRSF028983; BCP1; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cytoplasm; Cytoskeleton; DNA damage; DNA repair; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..308
FT                   /note="Protein BCCIP homolog"
FT                   /id="PRO_0000249690"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..53
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   308 AA;  35172 MW;  CACC0B559487E3D9 CRC64;
     MASNAKRRAL EPERLLEKHK EDEEDMEGDE SEESDDIEED ESEEDEEVNE EVNIDFEAYT
     ISDADYDGIK KLLKQLFLKA HVNISELTDL LIQQNHIGSA IKQAEGQDDS DDDEDDDHVF
     GVISLVNLTE RKGTACVEQI KELILSRCEE NCEQSLVEQF DKVLNDNSKP VGFLLSERFI
     NVPAQIALPM HQQLQKELAD SQRTNKPCGK CHYYLILSKT FMEATKTSKG SVGSQAKEEL
     MFANAEDEFF YEKALVKFNY SVQEESDTQL GGRWSFSDVP MKPLRTAMLV PAERMNSIMD
     KFKEYLSV
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024