ID   BCCP_CHLMU              Reviewed;         163 AA.
AC   Q9PKR5;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Biotin carboxyl carrier protein of acetyl-CoA carboxylase;
DE            Short=BCCP;
GN   Name=accB; OrderedLocusNames=TC_0399;
OS   Chlamydia muridarum (strain MoPn / Nigg).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=243161;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MoPn / Nigg;
RX   PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA   Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA   Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA   Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA   Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA   Salzberg S.L., Eisen J.A., Fraser C.M.;
RT   "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT   AR39.";
RL   Nucleic Acids Res. 28:1397-1406(2000).
CC   -!- FUNCTION: This protein is a component of the acetyl coenzyme A
CC       carboxylase complex; first, biotin carboxylase catalyzes the
CC       carboxylation of the carrier protein and then the transcarboxylase
CC       transfers the carboxyl group to form malonyl-CoA. {ECO:0000250}.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
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DR   EMBL; AE002160; AAF39256.1; -; Genomic_DNA.
DR   PIR; C81708; C81708.
DR   RefSeq; WP_010230365.1; NZ_CP027217.1.
DR   AlphaFoldDB; Q9PKR5; -.
DR   SMR; Q9PKR5; -.
DR   STRING; 243161.TC_0399; -.
DR   EnsemblBacteria; AAF39256; AAF39256; TC_0399.
DR   GeneID; 1245751; -.
DR   KEGG; cmu:TC_0399; -.
DR   eggNOG; COG0511; Bacteria.
DR   HOGENOM; CLU_016733_3_0_0; -.
DR   OMA; EVEYPCK; -.
DR   OrthoDB; 1938042at2; -.
DR   UniPathway; UPA00094; -.
DR   Proteomes; UP000000800; Chromosome.
DR   GO; GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
DR   GO; GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR001249; AcCoA_biotinCC.
DR   InterPro; IPR001882; Biotin_BS.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   PRINTS; PR01071; ACOABIOTINCC.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   TIGRFAMs; TIGR00531; BCCP; 1.
DR   PROSITE; PS00188; BIOTIN; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
PE   3: Inferred from homology;
KW   Biotin; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis;
KW   Lipid metabolism.
FT   CHAIN           1..163
FT                   /note="Biotin carboxyl carrier protein of acetyl-CoA
FT                   carboxylase"
FT                   /id="PRO_0000146802"
FT   DOMAIN          85..161
FT                   /note="Biotinyl-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01066"
FT   MOD_RES         127
FT                   /note="N6-biotinyllysine"
FT                   /evidence="ECO:0000250, ECO:0000255|PROSITE-
FT                   ProRule:PRU01066"
SQ   SEQUENCE   163 AA;  18084 MW;  8536D58B5CE11D3B CRC64;
     MDLKQIEKLM IAMGRNKMKR IAIKRDGFEL ELERDTGPNI QEPVFYDNRL FAGFTQERPI
     PSDQNLGNPI VKEVGEKKED KPVEGDFIVS PLVGTFYGAP SPESPAFVKP GDIVSEDTVV
     CIVEAMKVMN EVKAGMAGRV EEVLITNGDP VQFGSKLFRI VKA