ID   RSMB_CAEEL              Reviewed;         160 AA.
AC   P91918;
DT   28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Probable small nuclear ribonucleoprotein-associated protein B;
DE            Short=snRNP-B;
DE   AltName: Full=Sm protein B;
DE            Short=Sm-B;
DE            Short=SmB;
GN   Name=snr-2; ORFNames=W08E3.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000312|EMBL:CAB07132.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Plays a role in pre-mRNA splicing as a core component of the
CC       spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins
CC       (snRNPs), the building blocks of the spliceosome.
CC       {ECO:0000250|UniProtKB:P14678}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P14678}.
CC       Cytoplasm, cytosol {ECO:0000250|UniProtKB:P14678}.
CC   -!- SIMILARITY: Belongs to the snRNP SmB/SmN family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z92773; CAB07132.1; -; Genomic_DNA.
DR   PIR; T26289; T26289.
DR   RefSeq; NP_493348.1; NM_060947.4.
DR   AlphaFoldDB; P91918; -.
DR   SMR; P91918; -.
DR   BioGRID; 38599; 16.
DR   IntAct; P91918; 3.
DR   STRING; 6239.W08E3.1; -.
DR   EPD; P91918; -.
DR   PaxDb; P91918; -.
DR   PeptideAtlas; P91918; -.
DR   EnsemblMetazoa; W08E3.1.1; W08E3.1.1; WBGene00004915.
DR   GeneID; 173204; -.
DR   KEGG; cel:CELE_W08E3.1; -.
DR   UCSC; W08E3.1; c. elegans.
DR   CTD; 173204; -.
DR   WormBase; W08E3.1; CE14704; WBGene00004915; snr-2.
DR   eggNOG; KOG3168; Eukaryota.
DR   GeneTree; ENSGT00940000170258; -.
DR   HOGENOM; CLU_076902_1_1_1; -.
DR   InParanoid; P91918; -.
DR   OMA; DKHMNIL; -.
DR   OrthoDB; 1630470at2759; -.
DR   PhylomeDB; P91918; -.
DR   Reactome; R-CEL-111367; SLBP independent Processing of Histone Pre-mRNAs.
DR   Reactome; R-CEL-191859; snRNP Assembly.
DR   Reactome; R-CEL-72163; mRNA Splicing - Major Pathway.
DR   Reactome; R-CEL-72165; mRNA Splicing - Minor Pathway.
DR   Reactome; R-CEL-73856; RNA Polymerase II Transcription Termination.
DR   Reactome; R-CEL-77588; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs.
DR   PRO; PR:P91918; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00004915; Expressed in embryo and 3 other tissues.
DR   GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005685; C:U1 snRNP; IBA:GO_Central.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0071004; C:U2-type prespliceosome; IBA:GO_Central.
DR   GO; GO:0005687; C:U4 snRNP; IBA:GO_Central.
DR   GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR   GO; GO:0005682; C:U5 snRNP; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   InterPro; IPR001163; LSM_dom_euk/arc.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   Pfam; PF01423; LSM; 1.
DR   SMART; SM00651; Sm; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Ribonucleoprotein; RNA-binding; Spliceosome.
FT   CHAIN           1..160
FT                   /note="Probable small nuclear ribonucleoprotein-associated
FT                   protein B"
FT                   /id="PRO_0000125522"
FT   REGION          80..160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   160 AA;  16742 MW;  8427F8FFA0DAA9A1 CRC64;
     MTISKNNKMM AHLNYRMKII LQDGRTFIGF FKAFDKHMNI LLAECEEHRQ IKPKAGKKTD
     GEEKRILGLV LVRGEHIVSM TVDGPPPRDD DSVRLAKAGG AGGVGQAKPG GRGMPAMPGM
     PGMPPGGAPG GLSGAMRGHG GPGMAAMQPG YGGPPGGRPF