ID   RSMC_ALISL              Reviewed;         339 AA.
AC   B6EL06;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 2.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase C {ECO:0000255|HAMAP-Rule:MF_01862};
DE            EC=2.1.1.172 {ECO:0000255|HAMAP-Rule:MF_01862};
DE   AltName: Full=16S rRNA m2G1207 methyltransferase {ECO:0000255|HAMAP-Rule:MF_01862};
DE   AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RsmC {ECO:0000255|HAMAP-Rule:MF_01862};
GN   Name=rsmC {ECO:0000255|HAMAP-Rule:MF_01862}; OrderedLocusNames=VSAL_I2574;
OS   Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain
OS   LFI1238)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Aliivibrio.
OX   NCBI_TaxID=316275;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LFI1238;
RX   PubMed=19099551; DOI=10.1186/1471-2164-9-616;
RA   Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S., Bason N.,
RA   Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S.,
RA   Thurston S., Parkhill J., Willassen N.P., Thomson N.R.;
RT   "The genome sequence of the fish pathogen Aliivibrio salmonicida strain
RT   LFI1238 shows extensive evidence of gene decay.";
RL   BMC Genomics 9:616-616(2008).
CC   -!- FUNCTION: Specifically methylates the guanine in position 1207 of 16S
CC       rRNA in the 30S particle. {ECO:0000255|HAMAP-Rule:MF_01862}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC         N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:42736, Rhea:RHEA-COMP:10213, Rhea:RHEA-COMP:10214,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.172;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01862};
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_01862}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01862}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmC family.
CC       {ECO:0000255|HAMAP-Rule:MF_01862}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAQ80258.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; FM178379; CAQ80258.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_044583325.1; NC_011312.1.
DR   AlphaFoldDB; B6EL06; -.
DR   SMR; B6EL06; -.
DR   STRING; 316275.VSAL_I2574; -.
DR   EnsemblBacteria; CAQ80258; CAQ80258; VSAL_I2574.
DR   KEGG; vsa:VSAL_I2574; -.
DR   eggNOG; COG2813; Bacteria.
DR   HOGENOM; CLU_049581_0_1_6; -.
DR   OrthoDB; 1027015at2; -.
DR   Proteomes; UP000001730; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0052914; F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 2.
DR   HAMAP; MF_01862; 16SrRNA_methyltr_C; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR013675; Mtase_sm_N.
DR   InterPro; IPR023543; rRNA_ssu_MeTfrase_C.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   Pfam; PF05175; MTS; 1.
DR   Pfam; PF08468; MTS_N; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methyltransferase; rRNA processing; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..339
FT                   /note="Ribosomal RNA small subunit methyltransferase C"
FT                   /id="PRO_0000369688"
SQ   SEQUENCE   339 AA;  38127 MW;  77A7782F8B4EB06E CRC64;
     MSYSAPSQIT QRQLAYFEGK HVLIAGELND NFPLELDKHC ASTSIFTTNY GYYKQFSENP
     KINCYFGTEL IEESHADMIL LYWPKAKAEA EYLLTMLLAK LGKDTEIIVV GENRSGVKSV
     EKMFANFGPM NKLDSARRCS FYWGQCTETA PSFNLQDWFK EYQVQFKEHT IEVRSLPGVF
     SHGEFDKGSE LLLQTLPSLR GHVLDFGCGA GVLGSVMKTI NPKIHLDMVD ISAFAIASSI
     ETLKANGLEG NVFASDVYSD TKQNYQFIVS NPPFHAGLKT HYSSTEELLQ KAPQNLTHSG
     QMIFVANSFL QYPPIVEKVF GHCNTLAKNN KFRIYSAQK