RSMC_BUCAP
ID RSMC_BUCAP Reviewed; 336 AA.
AC Q8K9L5;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 15-NOV-2002, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Ribosomal RNA small subunit methyltransferase C {ECO:0000255|HAMAP-Rule:MF_01862};
DE EC=2.1.1.172 {ECO:0000255|HAMAP-Rule:MF_01862};
DE AltName: Full=16S rRNA m2G1207 methyltransferase {ECO:0000255|HAMAP-Rule:MF_01862};
DE AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RsmC {ECO:0000255|HAMAP-Rule:MF_01862};
GN Name=rsmC {ECO:0000255|HAMAP-Rule:MF_01862}; OrderedLocusNames=BUsg_319;
OS Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Buchnera.
OX NCBI_TaxID=198804;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sg;
RX PubMed=12089438; DOI=10.1126/science.1071278;
RA Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT "50 million years of genomic stasis in endosymbiotic bacteria.";
RL Science 296:2376-2379(2002).
CC -!- FUNCTION: Specifically methylates the guanine in position 1207 of 16S
CC rRNA in the 30S particle. {ECO:0000255|HAMAP-Rule:MF_01862}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:42736, Rhea:RHEA-COMP:10213, Rhea:RHEA-COMP:10214,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.172;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01862};
CC -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_01862}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01862}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmC family.
CC {ECO:0000255|HAMAP-Rule:MF_01862}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM67873.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE013218; AAM67873.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_011053840.1; NC_004061.1.
DR AlphaFoldDB; Q8K9L5; -.
DR SMR; Q8K9L5; -.
DR STRING; 198804.BUsg_319; -.
DR EnsemblBacteria; AAM67873; AAM67873; BUsg_319.
DR KEGG; bas:BUsg_319; -.
DR eggNOG; COG2813; Bacteria.
DR HOGENOM; CLU_1377143_0_0_6; -.
DR OMA; RHCQLWQ; -.
DR OrthoDB; 1027015at2; -.
DR Proteomes; UP000000416; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0052914; F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.150; -; 2.
DR HAMAP; MF_01862; 16SrRNA_methyltr_C; 1.
DR InterPro; IPR013675; Mtase_sm_N.
DR InterPro; IPR023543; rRNA_ssu_MeTfrase_C.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR Pfam; PF05175; MTS; 1.
DR Pfam; PF08468; MTS_N; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Methyltransferase; rRNA processing; S-adenosyl-L-methionine;
KW Transferase.
FT CHAIN 1..336
FT /note="Ribosomal RNA small subunit methyltransferase C"
FT /id="PRO_0000097488"
SQ SEQUENCE 336 AA; 38871 MW; 43BBC5E1D2535CFF CRC64;
MIFSKNSQLI LRHQKIFKNK IVFFSGNIED ELPINLLTIK TKIHLQKSQN FLKINNNKNI
TFYRKLLVSQ DTVQDCNILI YYWPKNKSEA RFQLFNILSF LPIKSEIFIV GSNSSGVKSA
KLILEESIKL KKIDNANHSI LMSGILINKT KFKLEKFFKI HIWKNLIIKS LPGVFGHKKI
DEGSKFIAST FSEKINGKIL DVGCGSGFLS VSILRKSPKC VVTMIDRKLS ALESSKATLD
ANFFKGEVLS SNIYSNIFKK FNMIVSNPPL HDDLKINFDI TKKIIFNSKK HLKKNGELRF
VTNHCFSYDF YLKKVFSEFH IMKKDNKYKV YQAFLK
