ID   RSMC_BUCBP              Reviewed;         326 AA.
AC   Q89AI2;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase C;
DE            EC=2.1.1.172;
DE   AltName: Full=16S rRNA m2G1207 methyltransferase;
DE   AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RsmC;
GN   Name=rsmC; OrderedLocusNames=bbp_305;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- FUNCTION: Specifically methylates the guanine in position 1207 of 16S
CC       rRNA in the 30S particle. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC         N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:42736, Rhea:RHEA-COMP:10213, Rhea:RHEA-COMP:10214,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.172;
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmC family.
CC       {ECO:0000305}.
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DR   EMBL; AE016826; AAO27030.1; -; Genomic_DNA.
DR   RefSeq; WP_011091431.1; NC_004545.1.
DR   AlphaFoldDB; Q89AI2; -.
DR   SMR; Q89AI2; -.
DR   STRING; 224915.bbp_305; -.
DR   PRIDE; Q89AI2; -.
DR   EnsemblBacteria; AAO27030; AAO27030; bbp_305.
DR   GeneID; 56470845; -.
DR   KEGG; bab:bbp_305; -.
DR   eggNOG; COG2813; Bacteria.
DR   HOGENOM; CLU_049581_0_1_6; -.
DR   OMA; RHCQLWQ; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0052914; F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.150; -; 2.
DR   InterPro; IPR013675; Mtase_sm_N.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   Pfam; PF05175; MTS; 1.
DR   Pfam; PF08468; MTS_N; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methyltransferase; Reference proteome; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..326
FT                   /note="Ribosomal RNA small subunit methyltransferase C"
FT                   /id="PRO_0000097489"
SQ   SEQUENCE   326 AA;  37481 MW;  F389256FC6EF6DF5 CRC64;
     MSSTKNVLIT GNTINFYMPN RPKLKVKMHT QCFNNFKNNQ KNSMFAIIFD VLVNKKIIQN
     SDVIIYIWPN SKLEALFQIN YIISLLSKTQ KIFFLGSNRS GIKCIQNLLK KWIIITKIDS
     SNHCILYSGI IVLKPIFLYE NFIKFNKWNN IVVKTIPGVF SYNNIDHGTK LLMSTCTKNL
     RWKTVLDIGC GSGVLSTYLA TIFPEIKLTL IDSNIAALES SKLTLTSNNV CGEIFPSNIY
     SNVHYQNFDL IISNPPLHVE NKLNFSIIDN IIKNSVKYLS NKGEIRIVTL KNVPCHKSFT
     LYFKKYTILK TSSHYKVYQA NYKDRV