ID   RSMC_BUCCC              Reviewed;         343 AA.
AC   Q057M1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase C;
DE            EC=2.1.1.172;
DE   AltName: Full=16S rRNA m2G1207 methyltransferase;
DE   AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RsmC;
GN   Name=rsmC; OrderedLocusNames=BCc_206;
OS   Buchnera aphidicola subsp. Cinara cedri (strain Cc).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=372461;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Cc;
RX   PubMed=17038625; DOI=10.1126/science.1130441;
RA   Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M., Michelena J.M.,
RA   Silva F.J., Moya A., Latorre A.;
RT   "A small microbial genome: the end of a long symbiotic relationship?";
RL   Science 314:312-313(2006).
CC   -!- FUNCTION: Specifically methylates the guanine in position 1207 of 16S
CC       rRNA in the 30S particle. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC         N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:42736, Rhea:RHEA-COMP:10213, Rhea:RHEA-COMP:10214,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.172;
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmC family.
CC       {ECO:0000305}.
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DR   EMBL; CP000263; ABJ90678.1; -; Genomic_DNA.
DR   RefSeq; WP_011672597.1; NC_008513.1.
DR   AlphaFoldDB; Q057M1; -.
DR   SMR; Q057M1; -.
DR   STRING; 372461.BCc_206; -.
DR   EnsemblBacteria; ABJ90678; ABJ90678; BCc_206.
DR   KEGG; bcc:BCc_206; -.
DR   eggNOG; COG2813; Bacteria.
DR   HOGENOM; CLU_049581_0_1_6; -.
DR   OMA; SARHCKL; -.
DR   OrthoDB; 1027015at2; -.
DR   Proteomes; UP000000669; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0052914; F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.150; -; 2.
DR   InterPro; IPR013675; Mtase_sm_N.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   Pfam; PF05175; MTS; 1.
DR   Pfam; PF08468; MTS_N; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methyltransferase; Reference proteome; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..343
FT                   /note="Ribosomal RNA small subunit methyltransferase C"
FT                   /id="PRO_0000369690"
SQ   SEQUENCE   343 AA;  40049 MW;  FAFEF2BCB6F4A48D CRC64;
     MNKTVIKTFQ ISKEYKILKK NFQLFKNKTT IISGIIPSVF LKINIIKRFI FYVNYFNLYL
     KILKKNSKNV IFNNFNHKNK LSSYKQLIFF LTKNKKEFKL HLTFLLSHIS KTCVIYVVGE
     KKCGINSISK IFSNYLIFKK IDYARTCSLY KAKIMKLPKF YLHKFINIYI WNNITIQSLP
     GVFGYKKIDT GSKLLISTFN KKINGKILDI GSGTGILSIA LAKKNPLIKI TLTDIYDAAI
     WCSKNNLIKN NLIGKVLFSD IYSHIKKRYD LIISNPPIHY NLKINLKILK KIIKNSKKHL
     KKKGELRIVI SSFISLKYII NFNKINFKIL LKNKSYTVIQ ITN