RSMC_SHESR
ID RSMC_SHESR Reviewed; 342 AA.
AC Q0HRD8;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 14-APR-2009, sequence version 2.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Ribosomal RNA small subunit methyltransferase C {ECO:0000255|HAMAP-Rule:MF_01862};
DE EC=2.1.1.172 {ECO:0000255|HAMAP-Rule:MF_01862};
DE AltName: Full=16S rRNA m2G1207 methyltransferase {ECO:0000255|HAMAP-Rule:MF_01862};
DE AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RsmC {ECO:0000255|HAMAP-Rule:MF_01862};
GN Name=rsmC {ECO:0000255|HAMAP-Rule:MF_01862};
GN OrderedLocusNames=Shewmr7_3335;
OS Shewanella sp. (strain MR-7).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=60481;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-7;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K.,
RA Konstantinidis K., Klappenbach J., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome 1 of Shewanella sp. MR-7.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Specifically methylates the guanine in position 1207 of 16S
CC rRNA in the 30S particle. {ECO:0000255|HAMAP-Rule:MF_01862}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:42736, Rhea:RHEA-COMP:10213, Rhea:RHEA-COMP:10214,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.172;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01862};
CC -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_01862}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01862}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmC family.
CC {ECO:0000255|HAMAP-Rule:MF_01862}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABI44317.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000444; ABI44317.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_041417271.1; NC_008322.1.
DR AlphaFoldDB; Q0HRD8; -.
DR SMR; Q0HRD8; -.
DR EnsemblBacteria; ABI44317; ABI44317; Shewmr7_3335.
DR KEGG; shm:Shewmr7_3335; -.
DR HOGENOM; CLU_049581_0_1_6; -.
DR OrthoDB; 1027015at2; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0052914; F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.40.50.150; -; 2.
DR HAMAP; MF_01862; 16SrRNA_methyltr_C; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR013675; Mtase_sm_N.
DR InterPro; IPR023543; rRNA_ssu_MeTfrase_C.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR Pfam; PF05175; MTS; 1.
DR Pfam; PF08468; MTS_N; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Methyltransferase; rRNA processing; S-adenosyl-L-methionine;
KW Transferase.
FT CHAIN 1..342
FT /note="Ribosomal RNA small subunit methyltransferase C"
FT /id="PRO_0000369781"
SQ SEQUENCE 342 AA; 37073 MW; 64CBC0B7C1DA5C2E CRC64;
MLTNPSQVII RNQETLSQHR VLVLNHEADS LPKALLDVAQ SVDALALDYH HYLHLAPQAN
AKLRCYFGHQ LPHQDKYDTV IVYFPKAKPL APYLFNLAAQ HLVADGQLLV VGENKGGVKS
LVKLLPKYFA TGVKLDNARH CLLFGSSIID TAPEIKLSDW TSQYQLATPQ GNITICNLVG
VFSEKHLDQG TELLLSHLPT LSGRVLDFGC GAGVIAAALL KAQPTLSLEC IDINAMALAS
CELTLAANGM TAKVYPSDGL AQTSGKFDGI ISNPPFHDGL ASTTSIAQSF VADSAKQLQS
KGIWQIVANR HLPYSDTIAA EFGQLTVPAE NNKYKLYSFQ QA
