ID   RSMD_BUCBP              Reviewed;         196 AA.
AC   Q89B29;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase D;
DE            EC=2.1.1.171;
DE   AltName: Full=16S rRNA m2G966 methyltransferase;
DE   AltName: Full=rRNA (guanine-N(2)-)-methyltransferase;
GN   Name=rsmD; OrderedLocusNames=bbp_025;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- FUNCTION: Specifically methylates the guanine in position 966 of 16S
CC       rRNA in the assembled 30S particle. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC         N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:23548, Rhea:RHEA-COMP:10211, Rhea:RHEA-COMP:10212,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.171;
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmD family.
CC       {ECO:0000305}.
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DR   EMBL; AE016826; AAO26768.1; -; Genomic_DNA.
DR   RefSeq; WP_011091169.1; NC_004545.1.
DR   AlphaFoldDB; Q89B29; -.
DR   SMR; Q89B29; -.
DR   STRING; 224915.bbp_025; -.
DR   EnsemblBacteria; AAO26768; AAO26768; bbp_025.
DR   GeneID; 56470569; -.
DR   KEGG; bab:bbp_025; -.
DR   eggNOG; COG0742; Bacteria.
DR   HOGENOM; CLU_075826_2_2_6; -.
DR   OMA; FNWLMPY; -.
DR   OrthoDB; 1827334at2; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0052913; F:16S rRNA (guanine(966)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR004398; RNA_MeTrfase_RsmD.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PIRSF; PIRSF004553; CHP00095; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00095; TIGR00095; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..196
FT                   /note="Ribosomal RNA small subunit methyltransferase D"
FT                   /id="PRO_0000216244"
SQ   SEQUENCE   196 AA;  22811 MW;  6967D74F4A27C737 CRC64;
     MKILKKKSKI TSIQIISGKY KNSRIPIINT KNLRPTTNYI RETLFNWISN EKIKKSHCLD
     CFSGSGALGI EAVSRYALSS TCIEIQKKAI FFLKKILIKL SITNVHVIRA NTIQWLKKPN
     KSYDIIFLDP PFKTTLLKQT IALLIKNNWL KNNALIYIEQ ENTLNKLITP PNNWILKKEK
     KTKKIHYSLY MNVNNF