位置:首页 > 蛋白库 > RSMG2_SYNFM
RSMG2_SYNFM
ID   RSMG2_SYNFM             Reviewed;         498 AA.
AC   A0LHE3;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase G 2;
DE            EC=2.1.1.170;
DE   AltName: Full=16S rRNA 7-methylguanosine methyltransferase 2;
DE            Short=16S rRNA m7G methyltransferase 2;
GN   Name=rsmG2; OrderedLocusNames=Sfum_1152;
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J., Sieber J.,
RA   Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically methylates the N7 position of guanine in
CC       position 527 of 16S rRNA. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)-
CC         methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:42732, Rhea:RHEA-COMP:10209, Rhea:RHEA-COMP:10210,
CC         ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74269,
CC         ChEBI:CHEBI:74480; EC=2.1.1.170;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the methyltransferase
CC       superfamily. RNA methyltransferase RsmG family. {ECO:0000305}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the class IV-like
CC       SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000478; ABK16845.1; -; Genomic_DNA.
DR   RefSeq; WP_011698016.1; NC_008554.1.
DR   AlphaFoldDB; A0LHE3; -.
DR   SMR; A0LHE3; -.
DR   STRING; 335543.Sfum_1152; -.
DR   EnsemblBacteria; ABK16845; ABK16845; Sfum_1152.
DR   KEGG; sfu:Sfum_1152; -.
DR   eggNOG; COG0357; Bacteria.
DR   eggNOG; COG0566; Bacteria.
DR   HOGENOM; CLU_547381_0_0_7; -.
DR   OMA; HPKALRA; -.
DR   OrthoDB; 1089708at2; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0070043; F:rRNA (guanine-N7-)-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   Gene3D; 3.40.50.150; -; 1.
DR   HAMAP; MF_00074; 16SrRNA_methyltr_G; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR003682; rRNA_ssu_MeTfrase_G.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   Pfam; PF02527; GidB; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
DR   TIGRFAMs; TIGR00138; rsmG_gidB; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methyltransferase; Reference proteome; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..498
FT                   /note="Ribosomal RNA small subunit methyltransferase G 2"
FT                   /id="PRO_0000342942"
FT   REGION          1..230
FT                   /note="Methyltransferase G"
FT   REGION          231..498
FT                   /note="Methyltransferase TrmH family"
FT   BINDING         89
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         94
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         154
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   498 AA;  55106 MW;  7A99CEFDBB8C0AC5 CRC64;
     MRNGTIRYPG SDAAPGPDEM SAILRRCGIR LAPARIGQLW TYHQLLREFN PELNLTRIHN
     FANMVLKLYV DSLLPMNLVE LPSPLMDLGT GPGMPGIPIK IAMPELEIVL AESRQKRAAF
     LKMAVERLKL EKVEVVGKSV GSSFEVPVKG VITRAVESVG ATLERIAGCL DRDGLAIFMK
     GPQCDAEIGE ALKRFRGEYR LWRDIHYTIP HTRNERRLVV FQRLGPPTRI RKETAMKRHG
     FRKIESENND LYRDIRKLLT SRGIRKQQRA LVSGSKQVHE TLRDFPDDCL AWIAPGQEMP
     PPEGAPGHMS WYQMAPALFE TLDVFGTRTP LLLIKVGEIE TWDPVEGFPA GCSVLVPFQD
     PENVGAVIRS AAAFGAVQVI LLRESAHPFH PKALRASGGA VLRMKLRNGP PLENLPENLP
     ILPLSAEGRD ITRHVFPAAF GLLPGLEGPG LPDNWRRKSF AIPICKDVES LNAATAAAIA
     LYAWSRSGSQ TKHSPAPA
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024