BCD_DROSU
ID BCD_DROSU Reviewed; 95 AA.
AC P55924;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Homeotic protein bicoid;
DE Flags: Fragment;
GN Name=bcd;
OS Drosophila subobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7241;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=H271;
RX PubMed=7587584; DOI=10.1007/bf00357688;
RA Terol J., Perez-Alonso M., de Frutos R.;
RT "Molecular characterization of the zerknullt region of the Antennapedia
RT complex of D. subobscura.";
RL Chromosoma 103:613-624(1995).
CC -!- FUNCTION: Bicoid is polarity protein that provides positional cues for
CC the development of head and thoracic segments. BCD regulates the
CC expression of zygotic genes, possibly through its homeodomain, and
CC inhibits the activity of other maternal gene products (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the paired homeobox family. Bicoid subfamily.
CC {ECO:0000305}.
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DR EMBL; X78058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P55924; -.
DR FlyBase; FBgn0015175; Dsub\bcd.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; RNA-binding;
KW Transcription; Transcription regulation.
FT CHAIN <1..95
FT /note="Homeotic protein bicoid"
FT /id="PRO_0000049015"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 42..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
SQ SEQUENCE 95 AA; 10250 MW; 1BD29EC08C267159 CRC64;
NLEPLKSHTV VGLDKSCDDG SSDDMSTGMR VLSGRGAFAK FGKPSAAQAQ PQPPPPPLGM
MHDTNQYQCT MDTIMQAYNP HRNAGGNTQF AYCFN