BCER_ALKHC
ID BCER_ALKHC Reviewed; 231 AA.
AC Q9K621;
DT 02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Sensory transduction protein BceR;
GN Name=bceR; OrderedLocusNames=BH3911;
OS Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS / JCM 9153 / C-125) (Bacillus halodurans).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=272558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT and genomic sequence comparison with Bacillus subtilis.";
RL Nucleic Acids Res. 28:4317-4331(2000).
CC -!- FUNCTION: Member of the two-component regulatory system BceS/BceR
CC involved in the regulation of bacitracin resistance. When activated by
CC BceS, binds to the upstream region of the bceAB promoter and up-
CC regulates the expression of these two genes (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- PTM: Phosphorylated by BceS. {ECO:0000305}.
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DR EMBL; BA000004; BAB07630.1; -; Genomic_DNA.
DR PIR; G84138; G84138.
DR RefSeq; WP_010900036.1; NC_002570.2.
DR AlphaFoldDB; Q9K621; -.
DR SMR; Q9K621; -.
DR STRING; 272558.10176536; -.
DR EnsemblBacteria; BAB07630; BAB07630; BAB07630.
DR KEGG; bha:BH3911; -.
DR eggNOG; COG0745; Bacteria.
DR HOGENOM; CLU_000445_30_3_9; -.
DR OMA; QIISEVW; -.
DR OrthoDB; 817710at2; -.
DR Proteomes; UP000001258; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR48111; PTHR48111; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; SSF46894; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1..231
FT /note="Sensory transduction protein BceR"
FT /id="PRO_0000081030"
FT DOMAIN 3..116
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DNA_BIND 127..225
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
FT MOD_RES 52
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 231 AA; 27061 MW; 97EEB755A8E09361 CRC64;
MFKIMLIEDD HTLFSEIKER LSQWSYDVFG VSNFEKVIEE FTSLKPDLVI IDIQLPKFDG
FHWCRMIRQH SNVPIIFLSS RDHPTDMVMS MQLGADDFIQ KPFHFDVLVA KIQAILRRVH
NYTSEQTQLK TWCGATIDYE SNTVSNHVGS IELSKNEFFI LKRLIERKNK IVTRDDLIRS
LWEDERFISD NTLTVNVNRL RKRLDELGLG AYIETKVGQG YMAKEDGNTH D
