BCHB_ARATH
ID BCHB_ARATH Reviewed; 2604 AA.
AC F4I9T0; Q9C6Q7; Q9C728;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=BEACH domain-containing protein B {ECO:0000303|PubMed:25618824};
DE AltName: Full=BEACH-domain homolog B {ECO:0000305};
GN Name=BCHB {ECO:0000303|PubMed:25618824};
GN OrderedLocusNames=At1g58230 {ECO:0000312|Araport:AT1G58230};
GN ORFNames=F16M22.8 {ECO:0000312|EMBL:AAG50953.1},
GN T18I24.16 {ECO:0000312|EMBL:AAG50767.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000312|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, NOMENCLATURE, AND DISRUPTION PHENOTYPE.
RX PubMed=25618824; DOI=10.1016/j.molp.2014.11.015;
RA Teh O.K., Hatsugai N., Tamura K., Fuji K., Tabata R., Yamaguchi K.,
RA Shingenobu S., Yamada M., Hasebe M., Sawa S., Shimada T.,
RA Hara-Nishimura I.;
RT "BEACH-domain proteins act together in a cascade to mediate vacuolar
RT protein trafficking and disease resistance in Arabidopsis.";
RL Mol. Plant 8:389-398(2015).
CC -!- FUNCTION: May be involved in the suppression of BCHC1 activity.
CC {ECO:0000305|PubMed:25618824}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:25618824}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG50767.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAG50953.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC073943; AAG50953.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC079131; AAG50767.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33518.1; -; Genomic_DNA.
DR PIR; H96615; H96615.
DR RefSeq; NP_564728.3; NM_104604.4.
DR AlphaFoldDB; F4I9T0; -.
DR SMR; F4I9T0; -.
DR STRING; 3702.AT1G58230.1; -.
DR iPTMnet; F4I9T0; -.
DR PaxDb; F4I9T0; -.
DR PRIDE; F4I9T0; -.
DR EnsemblPlants; AT1G58230.1; AT1G58230.1; AT1G58230.
DR GeneID; 842191; -.
DR Gramene; AT1G58230.1; AT1G58230.1; AT1G58230.
DR KEGG; ath:AT1G58230; -.
DR Araport; AT1G58230; -.
DR TAIR; locus:2015292; AT1G58230.
DR eggNOG; KOG1787; Eukaryota.
DR HOGENOM; CLU_000218_4_1_1; -.
DR InParanoid; F4I9T0; -.
DR OrthoDB; 101142at2759; -.
DR PRO; PR:F4I9T0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I9T0; baseline and differential.
DR Genevisible; F4I9T0; AT.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; -; 1.
DR Gene3D; 1.25.10.10; -; 1.
DR Gene3D; 2.130.10.10; -; 1.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF15787; DUF4704; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF48371; SSF48371; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR SUPFAM; SSF50978; SSF50978; 1.
DR SUPFAM; SSF81837; SSF81837; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..2604
FT /note="BEACH domain-containing protein B"
FT /id="PRO_0000434034"
FT DOMAIN 1761..1912
FT /note="BEACH-type PH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01119"
FT DOMAIN 1936..2226
FT /note="BEACH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00026"
FT REPEAT 2254..2293
FT /note="WD 1"
FT /evidence="ECO:0000255"
FT REPEAT 2368..2407
FT /note="WD 2"
FT /evidence="ECO:0000255"
FT REPEAT 2433..2474
FT /note="WD 3"
FT /evidence="ECO:0000255"
FT REPEAT 2476..2515
FT /note="WD 4"
FT /evidence="ECO:0000255"
FT REPEAT 2516..2557
FT /note="WD 5"
FT /evidence="ECO:0000255"
FT REPEAT 2558..2596
FT /note="WD 6"
FT /evidence="ECO:0000255"
SQ SEQUENCE 2604 AA; 292779 MW; D482E201DCD5192E CRC64;
MESDSVAGSA SSSDAAASHL PSVSVLLDAL EQSASTPRIA NGLSQRLLRS LQFSNENKLS
FKALNGACRV LRLACIQAKE SRKSGCVSPL VESSDCGVIV DSPHKKSDSS HTEDCWFECV
ESCVGIFTEF FSSTNDAKVY VLRSSVCVDC LFELFWEKAV RNNVMKLIID LMKIRPLCEE
DKSAKLQVCS KYLETFTQVK ERENDSVDLS VDLLAGMRDL IKSDSRYYQA LFREGECFLH
IVSLLNGNLD EANGEKLVLN VLQTLTSLLA NNDTSKFAFK ALAGKGYQTL QSLLLDFFQW
KPTQRLLDAL LDMLVDGKFD DKGSALIKNE DVIILYLNVL QKSSESLQCY GLNLFQQLLR
DSISNRASCV RAGMLHLLLD WFSLENDDSV ILKITQLTQT IGGHSISGKD IRKIFALLRS
ERVGNQQRYR SLLLACLLSM LNEKGPTGFF DMNGVESGIV IRTPVQWPAN KGFSFCCWLR
VESFPGDGKM GIFSFMSKNG KGCFAALGKD GLSYVSLNLK RQCVNVHTNL VCKKWHFICV
SHSIGRAFWG GSLLRCYVNG DLVSSERCSY PKVTDVLTSC LIGTRITLPH IQDNDGLESI
RDVFPFFGQI GPVYLFNDSL SSEQVQAIYS LGPSYMYAFL ENEMTCPFSD NPFPSGILDG
KDGLASKVSF GLNAQASDGR RLFNVSRVSD HLQERLAFEA DIMVGTQLCS RRLLQQIIYC
VGGISVFFPL ITQSDRCESE TLNEETSAMP TKERMTAEVI ELIASVLDEN PANQQQMHLL
AGFPILGFLL QSIQPKQLNL ETLSSLKHLF NVISSSGFAE QLVEDAISSI FLNPHIWLHA
AYNVQRELYM FLIQQLDNDP RLLGSLCRLP RVIDIVWNFY WESERYCKGS KPLMHPTRTI
AERPSRDEIH KIRLLLLSLG EMSLRHNISS GDVKALTAFF ETCQDVACIE DVLHMVIRAI
SQTSVLVSFL EQVNLIGGCH IFVDLLQRDY EPIRLLSLQF LGRLLYDVPS ERKGPKFFNL
AVGRTKSLSQ GHKKIGARTQ PIFLAMSDRL FQYPQTDNLR ATLFDVLLGG ASPKQVLQKH
NQVDKHRSKP SNSHFFLPQI FVFIFEFLSG CKDGLARMKI ISDILDLLDS NPMNVEALME
FGWSAWLTAS MKLDVIKDYR SELLNHDDLA LNEQHFVRGL FCVVLCHYIL SVKGGWQQLE
ETVNFILLQS EHNDVPYRSF LRDLYEDLIQ RLVELSSEDN IFLSHPCRDN VLYLLRLVDE
MLVREFGSRL LFPAISTDFS EDLLQLGNRE DPTLGLDESF QRFLTEEISR NTECQQSCTT
VTELMTNERW WNLYDNLWKI ICDINGRGPV KMSPKSLATG PSIGQRARGL VESLNVPAAE
MAAVVVSGGI GSALSGKMNK NVDKAMLLRG EKCPRIVFRL VTLYLCMSSL EKATRCVQQV
TSLLPSFLAA DDEQSKSRLH LFIGCLLYVR SQYGKLDDGA RFHVISHLIR ETVSCGKSIL
ATSGMNKDDS SDSGGIFKEM GSIQNLIHKD RVLAAVTDET TYMKTLISDR TRQVQALGER
NNETLSIECN SKKAFDGELQ NVLKTVVTWD ENRRVSVQLS HEEQQQNVTE KWIHMLRSLM
DERGPWSATP FPNNILNRWK LDRTEDSWRR RPKLRRNYHF DERLCHPPST STATENETSN
VINESKSGVI HIPEQMKKFL LKGIRRITDE GGSDSCENDS SQAEQSFMDT SADIQFSELV
RTSSGLKDVV QDKVDASSLE VGTSEVLTSV PCVLVTPKRK LAGWLAVMKN VLHFSGEFLV
EGTGGSAVFK NFSTSKGSDV TKAENKQNLV KWSSPYDSET FLDLESGNKN KKPLKKVKRH
RRWKIGKVKS VHWTRYLLQY TALEIFFQES VPPVFLNFAS QKNAKEVGML IVSTRNEFLF
PKNVPRDRTA MISFVDRRIA MEMAETARDR WRRREITNFE YLMILNTLAG RSYNDLTQYP
VFPWVVADYS SETLDFSKAS TFRDLSKPVG ALDTRRFEIF EDRYHSFSDP DIPSFYYGSH
YSSMGSVLYY LLRLEPFTSL HRSLQGGKFD HADRLFQSVE GSFRNCLSNT SDVKELIPEF
FYMPEFLVNS NSYHLGVKQD GEPLGEVCLP PWAKGSPEMF IARNREALES EYVSSHLHDW
IDLIFGHKQR GKPAVEAANI FYYLTYEGAV DVENMEDQLQ ISAIEDQIAN FGQTPIQIFR
KKHPRRGPPI PIAHPLYFAP ASINLSSILP ATTHSPSAVL YVGVVDSNIV LVNQGLTLSV
KIWLTTQLHS GGNFTFSSAQ DPFFGVGSDV LSPRNIGSPL ADNVELGSQC FAAMQMPLEN
FLVSCGNWEN SFHVISLTDG RVVQSIRHHK DVVSCVAVTA DSTILATGSY DTTVMVWDIL
RMRTPEKRVR NTHAEVLRKD IVIADAPSHI LCGHDDIITC LYVSTDLDIV ISGSKDGTCV
FHTLREGRYI RSLKHPSGSA VSKLAASHHG RIVLYGDDDL SLHLYSINGK HLASSESNGR
INCLELSKCG EFLVSAGDQG QIIVRSMNTL EVVKRYNGAG KIITSLTVTQ EECFLAGTKD
GALLVYSIEN PQHRKPSPIW SIKS
