ID   BCHM_RHOCA              Reviewed;         224 AA.
AC   P26236;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Magnesium-protoporphyrin O-methyltransferase;
DE            EC=2.1.1.11;
DE   AltName: Full=Magnesium-protoporphyrin IX methyltransferase;
GN   Name=bchM;
OS   Rhodobacter capsulatus (Rhodopseudomonas capsulata).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=1061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6744416; DOI=10.1016/0092-8674(84)90429-x;
RA   Youvan D.C., Bylina E.J., Alberti M., Begusch H., Hearst J.E.;
RT   "Nucleotide and deduced polypeptide sequences of the photosynthetic
RT   reaction-center, B870 antenna, and flanking polypeptides from R.
RT   capsulata.";
RL   Cell 37:949-957(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19.
RX   PubMed=2203738; DOI=10.1128/jb.172.9.5001-5010.1990;
RA   Yang Z.M., Bauer C.E.;
RT   "Rhodobacter capsulatus genes involved in early steps of the
RT   bacteriochlorophyll biosynthetic pathway.";
RL   J. Bacteriol. 172:5001-5010(1990).
RN   [3]
RP   CHARACTERIZATION.
RX   PubMed=8071204; DOI=10.1128/jb.176.17.5290-5296.1994;
RA   Bollivar D.W., Jiang Z.Y., Bauer C.E., Beale S.I.;
RT   "Heterologous expression of the bchM gene product from Rhodobacter
RT   capsulatus and demonstration that it encodes S-adenosyl-L-methionine:Mg-
RT   protoporphyrin IX methyltransferase.";
RL   J. Bacteriol. 176:5290-5296(1994).
CC   -!- FUNCTION: Converts Mg-protoporphyrin IX to Mg-protoporphyrin IX
CC       methylester using S-adenosyl-L-methionine as a cofactor.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Mg-protoporphyrin IX + S-adenosyl-L-methionine = Mg-
CC         protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:17809, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:60491, ChEBI:CHEBI:60492; EC=2.1.1.11;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU00889};
CC   -!- PATHWAY: Porphyrin-containing compound metabolism; bacteriochlorophyll
CC       biosynthesis (light-independent).
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. Magnesium protoporphyrin O-methyltransferase family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00889}.
CC   -!- CAUTION: Was originally thought to be involved in formation of the
CC       cyclopentone ring of protochlorophyllide from Mg-protoporphyrin IX
CC       monomethyl ester. {ECO:0000305|PubMed:6744416}.
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DR   EMBL; Z11165; CAA77522.1; -; Genomic_DNA.
DR   EMBL; K01183; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; M34843; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; A28988; A28988.
DR   RefSeq; WP_013066405.1; NZ_VIBE01000010.1.
DR   AlphaFoldDB; P26236; -.
DR   SMR; P26236; -.
DR   IntAct; P26236; 1.
DR   MINT; P26236; -.
DR   GeneID; 31489607; -.
DR   OMA; LDVFIHY; -.
DR   BRENDA; 2.1.1.11; 5381.
DR   UniPathway; UPA00671; -.
DR   GO; GO:0046406; F:magnesium protoporphyrin IX methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030494; P:bacteriochlorophyll biosynthetic process; IMP:CACAO.
DR   GO; GO:0036070; P:light-independent bacteriochlorophyll biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR010251; Mg_prot_MeTrfase.
DR   InterPro; IPR010940; Mg_prot_MeTrfase_C.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   Pfam; PF07109; Mg-por_mtran_C; 1.
DR   Pfam; PF05175; MTS; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR02021; BchM-ChlM; 1.
DR   PROSITE; PS51556; SAM_MT_MG_PIX; 1.
PE   1: Evidence at protein level;
KW   Bacteriochlorophyll biosynthesis; Chlorophyll biosynthesis;
KW   Methyltransferase; Photosynthesis; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..224
FT                   /note="Magnesium-protoporphyrin O-methyltransferase"
FT                   /id="PRO_0000204420"
SQ   SEQUENCE   224 AA;  25225 MW;  B32BB9B3DD3CF9EC CRC64;
     MPSDYAEIRN RVEHYFDRTA TRAWARLTTA DEKVSKVRQT VREGRDTMRA VMLSRLPDDL
     TGCRVMDAGC GTGLTTVELA RRGADVVAVD ISPQLIDIAK DRLPPELRGK VSFHVGDMAD
     PALGQFDYVV AMDSLIYYRA PDIGRVLTEL GKRTHSAIVF TVAPKTAFLM AFWWLGKLFP
     RSNRSPVMIP HALDKLQRHA GDSLIKIDRV ARGFYISECL EYRP