BCHP_RHOCB
ID BCHP_RHOCB Reviewed; 391 AA.
AC P26172; D5ANT4;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1992, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Geranylgeranyl diphosphate reductase;
DE EC=1.3.1.83;
DE AltName: Full=Geranylgeranyl reductase;
GN Name=bchP; OrderedLocusNames=RCAP_rcc00673;
OS Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Rhodobacter.
OX NCBI_TaxID=272942;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RA Burke D.H., Alberti M., Armstrong G.A., Hearst J.E.;
RL Submitted (NOV-1991) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX PubMed=20418398; DOI=10.1128/jb.00366-10;
RA Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V.,
RA Haselkorn R.;
RT "Complete genome sequence of the photosynthetic purple nonsulfur bacterium
RT Rhodobacter capsulatus SB 1003.";
RL J. Bacteriol. 192:3545-3546(2010).
CC -!- FUNCTION: Catalyzes the stepwise hydrogenation of geranylgeraniol to
CC phytol during bacteriochlorophyll A (BchlA) biosynthesis.
CC {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3 NADP(+) + phytyl diphosphate = geranylgeranyl diphosphate +
CC 3 H(+) + 3 NADPH; Xref=Rhea:RHEA:26229, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57533, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:75434; EC=1.3.1.83;
CC -!- PATHWAY: Porphyrin-containing compound metabolism; bacteriochlorophyll
CC biosynthesis (light-independent).
CC -!- SIMILARITY: Belongs to the geranylgeranyl reductase family. ChlP
CC subfamily. {ECO:0000305}.
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DR EMBL; Z11165; CAA77534.1; -; Genomic_DNA.
DR EMBL; CP001312; ADE84438.1; -; Genomic_DNA.
DR PIR; S17818; S17818.
DR RefSeq; WP_013066417.1; NC_014034.1.
DR AlphaFoldDB; P26172; -.
DR SMR; P26172; -.
DR STRING; 272942.RCAP_rcc00673; -.
DR EnsemblBacteria; ADE84438; ADE84438; RCAP_rcc00673.
DR GeneID; 31489619; -.
DR KEGG; rcp:RCAP_rcc00673; -.
DR eggNOG; COG0644; Bacteria.
DR HOGENOM; CLU_024648_3_1_5; -.
DR OMA; GMCRREV; -.
DR OrthoDB; 1770293at2; -.
DR BioCyc; MetaCyc:MON-13251; -.
DR UniPathway; UPA00671; -.
DR Proteomes; UP000002361; Chromosome.
DR GO; GO:0102067; F:geranylgeranyl diphosphate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0045550; F:geranylgeranyl reductase activity; IEA:InterPro.
DR GO; GO:0036070; P:light-independent bacteriochlorophyll biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; -; 1.
DR InterPro; IPR010253; BchP_ChlP_pln/prok.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR02023; BchP-ChlP; 1.
DR TIGRFAMs; TIGR02032; GG-red-SF; 1.
PE 3: Inferred from homology;
KW Bacteriochlorophyll biosynthesis; Chlorophyll biosynthesis; NADP;
KW Oxidoreductase; Photosynthesis; Reference proteome.
FT CHAIN 1..391
FT /note="Geranylgeranyl diphosphate reductase"
FT /id="PRO_0000219665"
SQ SEQUENCE 391 AA; 43245 MW; AB1170C9B14C7525 CRC64;
MKYDAFVVGG GPAGSTAAWD MARAGLKVAL LDRAGRIKPC GGAIPPRLIR DFDIPDHLLV
AKITSARMIS PTGRFVDIPI ENGFVGMVDR EDYDEWLRER AGKAGAERLT GTWLRIERDS
GKTVVVWRDK VTGEEMKAET RVVIGADGAN SQVRNEVPAT KIPLVFAYHE IIKAPTTVAN
YDPTRCDVYY DGRISPDFYG WVFPHGKTAS IGMGTELPDV SLKDCTTLLR QMSGLDKEET
IRKEGAPIPL QPLDVWDNGK DVVLSGDAAG VVAPSSGEGI YYAHAGGRYA AEAAMAFLKS
GKPADLKLAR AGFMKEHGTV FKVLRMMQDK YYHSDDRRER FVSLCHDVDV QRMTFESYMN
KKMTKFQPLK NLKIGFKNLA HLSGLVPPQW T