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BCHP_RHOCB
ID   BCHP_RHOCB              Reviewed;         391 AA.
AC   P26172; D5ANT4;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Geranylgeranyl diphosphate reductase;
DE            EC=1.3.1.83;
DE   AltName: Full=Geranylgeranyl reductase;
GN   Name=bchP; OrderedLocusNames=RCAP_rcc00673;
OS   Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=272942;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RA   Burke D.H., Alberti M., Armstrong G.A., Hearst J.E.;
RL   Submitted (NOV-1991) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX   PubMed=20418398; DOI=10.1128/jb.00366-10;
RA   Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V.,
RA   Haselkorn R.;
RT   "Complete genome sequence of the photosynthetic purple nonsulfur bacterium
RT   Rhodobacter capsulatus SB 1003.";
RL   J. Bacteriol. 192:3545-3546(2010).
CC   -!- FUNCTION: Catalyzes the stepwise hydrogenation of geranylgeraniol to
CC       phytol during bacteriochlorophyll A (BchlA) biosynthesis.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3 NADP(+) + phytyl diphosphate = geranylgeranyl diphosphate +
CC         3 H(+) + 3 NADPH; Xref=Rhea:RHEA:26229, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57533, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC         ChEBI:CHEBI:75434; EC=1.3.1.83;
CC   -!- PATHWAY: Porphyrin-containing compound metabolism; bacteriochlorophyll
CC       biosynthesis (light-independent).
CC   -!- SIMILARITY: Belongs to the geranylgeranyl reductase family. ChlP
CC       subfamily. {ECO:0000305}.
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DR   EMBL; Z11165; CAA77534.1; -; Genomic_DNA.
DR   EMBL; CP001312; ADE84438.1; -; Genomic_DNA.
DR   PIR; S17818; S17818.
DR   RefSeq; WP_013066417.1; NC_014034.1.
DR   AlphaFoldDB; P26172; -.
DR   SMR; P26172; -.
DR   STRING; 272942.RCAP_rcc00673; -.
DR   EnsemblBacteria; ADE84438; ADE84438; RCAP_rcc00673.
DR   GeneID; 31489619; -.
DR   KEGG; rcp:RCAP_rcc00673; -.
DR   eggNOG; COG0644; Bacteria.
DR   HOGENOM; CLU_024648_3_1_5; -.
DR   OMA; GMCRREV; -.
DR   OrthoDB; 1770293at2; -.
DR   BioCyc; MetaCyc:MON-13251; -.
DR   UniPathway; UPA00671; -.
DR   Proteomes; UP000002361; Chromosome.
DR   GO; GO:0102067; F:geranylgeranyl diphosphate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045550; F:geranylgeranyl reductase activity; IEA:InterPro.
DR   GO; GO:0036070; P:light-independent bacteriochlorophyll biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR010253; BchP_ChlP_pln/prok.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR02023; BchP-ChlP; 1.
DR   TIGRFAMs; TIGR02032; GG-red-SF; 1.
PE   3: Inferred from homology;
KW   Bacteriochlorophyll biosynthesis; Chlorophyll biosynthesis; NADP;
KW   Oxidoreductase; Photosynthesis; Reference proteome.
FT   CHAIN           1..391
FT                   /note="Geranylgeranyl diphosphate reductase"
FT                   /id="PRO_0000219665"
SQ   SEQUENCE   391 AA;  43245 MW;  AB1170C9B14C7525 CRC64;
     MKYDAFVVGG GPAGSTAAWD MARAGLKVAL LDRAGRIKPC GGAIPPRLIR DFDIPDHLLV
     AKITSARMIS PTGRFVDIPI ENGFVGMVDR EDYDEWLRER AGKAGAERLT GTWLRIERDS
     GKTVVVWRDK VTGEEMKAET RVVIGADGAN SQVRNEVPAT KIPLVFAYHE IIKAPTTVAN
     YDPTRCDVYY DGRISPDFYG WVFPHGKTAS IGMGTELPDV SLKDCTTLLR QMSGLDKEET
     IRKEGAPIPL QPLDVWDNGK DVVLSGDAAG VVAPSSGEGI YYAHAGGRYA AEAAMAFLKS
     GKPADLKLAR AGFMKEHGTV FKVLRMMQDK YYHSDDRRER FVSLCHDVDV QRMTFESYMN
     KKMTKFQPLK NLKIGFKNLA HLSGLVPPQW T
 
 
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