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RSMN_MACFA
ID   RSMN_MACFA              Reviewed;         240 AA.
AC   Q60HD3;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Small nuclear ribonucleoprotein-associated protein N;
DE            Short=snRNP-N;
DE   AltName: Full=Sm protein N;
DE            Short=Sm-N;
DE            Short=SmN;
GN   Name=SNRPN; ORFNames=QccE-19338, QflA-11237, QtrA-10022;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RA   Kusuda J., Osada N., Tanuma R., Hirata M., Sugano S., Hashimoto K.;
RT   "Isolation and characterization of cDNA for macaque neurological disease
RT   genes.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Frontal cortex, and Temporal cortex;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in tissue-specific alternative RNA processing
CC       events. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with TDRD3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- MISCELLANEOUS: Encoded on a bicistronic transcript that code for two
CC       proteins, SNRPN and SNURF.
CC   -!- SIMILARITY: Belongs to the snRNP SmB/SmN family. {ECO:0000305}.
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DR   EMBL; AB125194; BAD51982.1; -; mRNA.
DR   EMBL; AB169720; BAE01801.1; -; mRNA.
DR   EMBL; AB169895; BAE01976.1; -; mRNA.
DR   RefSeq; NP_001274613.1; NM_001287684.1.
DR   RefSeq; XP_005559000.1; XM_005558943.2.
DR   RefSeq; XP_015307952.1; XM_015452466.1.
DR   RefSeq; XP_015307953.1; XM_015452467.1.
DR   RefSeq; XP_015307955.1; XM_015452469.1.
DR   AlphaFoldDB; Q60HD3; -.
DR   SMR; Q60HD3; -.
DR   STRING; 9541.XP_005558994.1; -.
DR   Ensembl; ENSMFAT00000077666; ENSMFAP00000056451; ENSMFAG00000042235.
DR   GeneID; 102133696; -.
DR   KEGG; mcf:102133696; -.
DR   CTD; 6638; -.
DR   VEuPathDB; HostDB:ENSMFAG00000042235; -.
DR   eggNOG; KOG3168; Eukaryota.
DR   GeneTree; ENSGT00940000158222; -.
DR   OMA; FAPQRPG; -.
DR   OrthoDB; 1630470at2759; -.
DR   Proteomes; UP000233100; Chromosome 7.
DR   Bgee; ENSMFAG00000042235; Expressed in cerebellum and 13 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR001163; LSM_dom_euk/arc.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR017131; snRNP-assoc_SmB/SmN.
DR   Pfam; PF01423; LSM; 1.
DR   PIRSF; PIRSF037187; snRNP_SmB/SmN; 1.
DR   SMART; SM00651; Sm; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
PE   2: Evidence at transcript level;
KW   Methylation; Nucleus; Reference proteome; Repeat; Ribonucleoprotein;
KW   RNA-binding.
FT   CHAIN           1..240
FT                   /note="Small nuclear ribonucleoprotein-associated protein
FT                   N"
FT                   /id="PRO_0000249874"
FT   REPEAT          175..181
FT   REPEAT          191..196
FT   REPEAT          216..221
FT   REPEAT          222..228
FT   REPEAT          230..236
FT   REGION          163..240
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          175..236
FT                   /note="Repeat-rich region"
FT   COMPBIAS        169..240
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         108
FT                   /note="Asymmetric dimethylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P14678"
FT   MOD_RES         108
FT                   /note="Dimethylated arginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P14678"
FT   MOD_RES         108
FT                   /note="Omega-N-methylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P63163"
FT   MOD_RES         112
FT                   /note="Asymmetric dimethylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P14678"
FT   MOD_RES         112
FT                   /note="Dimethylated arginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P14678"
FT   MOD_RES         112
FT                   /note="Omega-N-methylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P14678"
FT   MOD_RES         147
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0000250|UniProtKB:P14678"
FT   MOD_RES         172
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0000250|UniProtKB:P63162"
SQ   SEQUENCE   240 AA;  24614 MW;  9A176D043561474C CRC64;
     MTVGKSSKML QHIDYRMRCI LQDGRIFIGT FKAFDKHMNL ILCDCDEFRK IKPKNAKQPE
     REEKRVLGLV LLRGENLVSM TVEGPPPKDT GIARVPLAGA AGGPGVGRAA GRGVPAGVPI
     PQAPAGLAGP VRGVGGPSQQ VMTPQGRGTV AAAAVAATAS IAGAPTQYPP GRGTPPPPVG
     RATPPPGIMA PPPGMRPPMG PPIGLPPARG TPIGMPPPGM RPPPPGIRGP PPPGMRPPRP
 
 
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