RSMN_PONAB
ID RSMN_PONAB Reviewed; 240 AA.
AC Q5R6I0;
DT 19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Small nuclear ribonucleoprotein-associated protein N;
DE Short=snRNP-N;
DE AltName: Full=Sm protein N;
DE Short=Sm-N;
DE Short=SmN;
GN Name=SNRPN;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex, and Heart;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in tissue-specific alternative RNA processing
CC events. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with TDRD3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- MISCELLANEOUS: Encoded on a bicistronic transcript that code for two
CC proteins, SNRPN and SNURF.
CC -!- SIMILARITY: Belongs to the snRNP SmB/SmN family. {ECO:0000305}.
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DR EMBL; CR860509; CAH92634.1; -; mRNA.
DR EMBL; CR861292; CAH93359.1; -; mRNA.
DR RefSeq; NP_001127571.1; NM_001134099.1.
DR AlphaFoldDB; Q5R6I0; -.
DR SMR; Q5R6I0; -.
DR STRING; 9601.ENSPPYP00000007107; -.
DR PRIDE; Q5R6I0; -.
DR Ensembl; ENSPPYT00000059711; ENSPPYP00000031932; ENSPPYG00000006269.
DR GeneID; 100174649; -.
DR KEGG; pon:100174649; -.
DR CTD; 8926; -.
DR eggNOG; KOG3168; Eukaryota.
DR GeneTree; ENSGT00940000158222; -.
DR HOGENOM; CLU_076902_1_0_1; -.
DR InParanoid; Q5R6I0; -.
DR OMA; FAPQRPG; -.
DR OrthoDB; 1630470at2759; -.
DR TreeFam; TF314232; -.
DR Proteomes; UP000001595; Chromosome 15.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR001163; LSM_dom_euk/arc.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR017131; snRNP-assoc_SmB/SmN.
DR Pfam; PF01423; LSM; 1.
DR PIRSF; PIRSF037187; snRNP_SmB/SmN; 1.
DR SMART; SM00651; Sm; 1.
DR SUPFAM; SSF50182; SSF50182; 1.
PE 2: Evidence at transcript level;
KW Methylation; Nucleus; Reference proteome; Repeat; Ribonucleoprotein;
KW RNA-binding.
FT CHAIN 1..240
FT /note="Small nuclear ribonucleoprotein-associated protein
FT N"
FT /id="PRO_0000249875"
FT REPEAT 175..181
FT REPEAT 191..196
FT REPEAT 216..221
FT REPEAT 222..228
FT REPEAT 230..236
FT REGION 163..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..236
FT /note="Repeat-rich region"
FT COMPBIAS 169..240
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 108
FT /note="Asymmetric dimethylarginine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P14678"
FT MOD_RES 108
FT /note="Dimethylated arginine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P14678"
FT MOD_RES 108
FT /note="Omega-N-methylarginine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P63163"
FT MOD_RES 112
FT /note="Asymmetric dimethylarginine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P14678"
FT MOD_RES 112
FT /note="Dimethylated arginine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P14678"
FT MOD_RES 112
FT /note="Omega-N-methylarginine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P14678"
FT MOD_RES 147
FT /note="Omega-N-methylarginine"
FT /evidence="ECO:0000250|UniProtKB:P14678"
FT MOD_RES 172
FT /note="Omega-N-methylarginine"
FT /evidence="ECO:0000250|UniProtKB:P63162"
SQ SEQUENCE 240 AA; 24614 MW; 9A176D043561474C CRC64;
MTVGKSSKML QHIDYRMRCI LQDGRIFIGT FKAFDKHMNL ILCDCDEFRK IKPKNAKQPE
REEKRVLGLV LLRGENLVSM TVEGPPPKDT GIARVPLAGA AGGPGVGRAA GRGVPAGVPI
PQAPAGLAGP VRGVGGPSQQ VMTPQGRGTV AAAAVAATAS IAGAPTQYPP GRGTPPPPVG
RATPPPGIMA PPPGMRPPMG PPIGLPPARG TPIGMPPPGM RPPPPGIRGP PPPGMRPPRP
