ID   RSOA_BACSU              Reviewed;          79 AA.
AC   C0H3R4;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Sigma-O factor regulatory protein RsoA;
GN   Name=rsoA; Synonyms=yvrHa; OrderedLocusNames=BSU33222;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   FUNCTION AS A SIGO ACCESSORY PROTEIN, AND INDUCTION.
RC   STRAIN=168 / CU1065;
RX   PubMed=18573182; DOI=10.1111/j.1365-2958.2008.06331.x;
RA   MacLellan S.R., Wecke T., Helmann J.D.;
RT   "A previously unidentified sigma factor and two accessory proteins regulate
RT   oxalate decarboxylase expression in Bacillus subtilis.";
RL   Mol. Microbiol. 69:954-967(2008).
RN   [3]
RP   FUNCTION IN OXDC INDUCTION.
RC   STRAIN=168 / CU1065;
RX   PubMed=19047353; DOI=10.1128/jb.01435-08;
RA   MacLellan S.R., Helmann J.D., Antelmann H.;
RT   "The yvrI alternative sigma factor is essential for acid stress induction
RT   of oxalate decarboxylase in Bacillus subtilis.";
RL   J. Bacteriol. 191:931-939(2009).
CC   -!- FUNCTION: Together with RNA polymerase sigma factor SigO, positively
CC       regulates the expression of at least three operons, including oxdC-
CC       yvrL, sigO-rsoA and yvrJ. Required for the acid stress-dependent
CC       induction of the oxalate decarboxylase oxdC.
CC       {ECO:0000269|PubMed:18573182, ECO:0000269|PubMed:19047353}.
CC   -!- INTERACTION:
CC       C0H3R4; P37871: rpoC; NbExp=3; IntAct=EBI-15816929, EBI-5244361;
CC       C0H3R4; O34843: sigO; NbExp=2; IntAct=EBI-15816929, EBI-15816883;
CC   -!- INDUCTION: Positively regulated by SigO. {ECO:0000269|PubMed:18573182}.
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DR   EMBL; AL009126; CAX52693.1; -; Genomic_DNA.
DR   RefSeq; WP_003228484.1; NZ_JNCM01000033.1.
DR   RefSeq; YP_003097787.1; NC_000964.3.
DR   AlphaFoldDB; C0H3R4; -.
DR   SMR; C0H3R4; -.
DR   DIP; DIP-49020N; -.
DR   IntAct; C0H3R4; 2.
DR   STRING; 224308.BSU33222; -.
DR   PaxDb; C0H3R4; -.
DR   EnsemblBacteria; CAX52693; CAX52693; BSU_33222.
DR   GeneID; 8302938; -.
DR   KEGG; bsu:BSU33222; -.
DR   PATRIC; fig|224308.179.peg.3604; -.
DR   OMA; MLLCQEV; -.
DR   BioCyc; BSUB:BSU33222-MON; -.
DR   Proteomes; UP000001570; Chromosome.
PE   1: Evidence at protein level;
KW   Activator; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..79
FT                   /note="Sigma-O factor regulatory protein RsoA"
FT                   /id="PRO_0000378488"
SQ   SEQUENCE   79 AA;  9546 MW;  675BBF77D37C088F CRC64;
     MDGQFEQKKK QKDETYDIEH LIACFSPMIR KKLSNTSYQE REDLEQELKI KMFEKADMLL
     CQDVPGFWEF ILYMVDENS