RSP14_MOUSE
ID RSP14_MOUSE Reviewed; 341 AA.
AC Q9D3W1;
DT 29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Radial spoke head 14 homolog;
DE AltName: Full=Rhabdoid tumor deletion region protein 1;
GN Name=Rsph14 {ECO:0000312|MGI:MGI:1918486}; Synonyms=Rtdr1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the flagellar radial spoke RSP14 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK017008; BAB30547.1; -; mRNA.
DR EMBL; AC142500; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH466553; EDL31936.1; -; Genomic_DNA.
DR EMBL; BC147792; AAI47793.1; -; mRNA.
DR EMBL; BC147801; AAI47802.1; -; mRNA.
DR CCDS; CCDS48596.1; -.
DR RefSeq; NP_001157005.1; NM_001163533.1.
DR RefSeq; NP_001157006.1; NM_001163534.1.
DR RefSeq; NP_001157007.1; NM_001163535.1.
DR RefSeq; NP_082006.1; NM_027730.1.
DR AlphaFoldDB; Q9D3W1; -.
DR SMR; Q9D3W1; -.
DR STRING; 10090.ENSMUSP00000131632; -.
DR PhosphoSitePlus; Q9D3W1; -.
DR MaxQB; Q9D3W1; -.
DR PaxDb; Q9D3W1; -.
DR PRIDE; Q9D3W1; -.
DR ProteomicsDB; 256937; -.
DR Antibodypedia; 9251; 167 antibodies from 26 providers.
DR Ensembl; ENSMUST00000009214; ENSMUSP00000009214; ENSMUSG00000009070.
DR Ensembl; ENSMUST00000179546; ENSMUSP00000136715; ENSMUSG00000009070.
DR GeneID; 71236; -.
DR KEGG; mmu:71236; -.
DR UCSC; uc007fps.1; mouse.
DR CTD; 27156; -.
DR MGI; MGI:1918486; Rsph14.
DR VEuPathDB; HostDB:ENSMUSG00000009070; -.
DR eggNOG; KOG0167; Eukaryota.
DR GeneTree; ENSGT00500000044989; -.
DR HOGENOM; CLU_057538_0_0_1; -.
DR OMA; DYLHDPE; -.
DR OrthoDB; 1376007at2759; -.
DR PhylomeDB; Q9D3W1; -.
DR BioGRID-ORCS; 71236; 1 hit in 71 CRISPR screens.
DR ChiTaRS; Rsph14; mouse.
DR PRO; PR:Q9D3W1; -.
DR Proteomes; UP000000589; Chromosome 10.
DR RNAct; Q9D3W1; protein.
DR Bgee; ENSMUSG00000009070; Expressed in spermatocyte and 40 other tissues.
DR ExpressionAtlas; Q9D3W1; baseline and differential.
DR Genevisible; Q9D3W1; MM.
DR Gene3D; 1.25.10.10; -; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR042856; RSP14.
DR PANTHER; PTHR15599:SF1; PTHR15599:SF1; 1.
DR SMART; SM00185; ARM; 4.
DR SUPFAM; SSF48371; SSF48371; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat.
FT CHAIN 1..341
FT /note="Radial spoke head 14 homolog"
FT /id="PRO_0000432959"
FT REPEAT 16..55
FT /note="ARM 1"
FT /evidence="ECO:0000255"
FT REPEAT 57..96
FT /note="ARM 2"
FT /evidence="ECO:0000255"
FT REPEAT 99..138
FT /note="ARM 3"
FT /evidence="ECO:0000255"
FT REPEAT 139..178
FT /note="ARM 4"
FT /evidence="ECO:0000255"
FT REPEAT 180..217
FT /note="ARM 5"
FT /evidence="ECO:0000255"
FT REPEAT 219..258
FT /note="ARM 6"
FT /evidence="ECO:0000255"
FT REPEAT 260..300
FT /note="ARM 7"
FT /evidence="ECO:0000255"
FT REPEAT 302..339
FT /note="ARM 8"
FT /evidence="ECO:0000255"
SQ SEQUENCE 341 AA; 37809 MW; D0093868603C9B9B CRC64;
MAHARISMYM PPDIDPTKAA IAYGCRALSK LNEELQSRDL LTRQKALVAL CDLMHDPEYV
YEAINIGCLE SLKTLLQDDD NLVRIKTTEV LYIMATHYVG RVGFLKHDII QALSLLLSDH
QTLCRENLHQ AYKHLAQLPK GAQGIVQSGL IPSLVRKLQK EEDHIQEIIL DTLALCLQED
ATEALESQAV PCLKEKLLSQ NSEIRSKAAR ALIAISIPLD GKNQVWKNKV IPILVTLLSD
TDEEVKANAA GALMHATVTT EGKYAALDAN AIEPLLELLS TNPKTKLCLN ATKALTMLAE
APEGRKLLLS HVPIFRYLLA HKNEAIQRAA EVAIKVIEWK P
