ID   RSPH9_BOVIN             Reviewed;         276 AA.
AC   Q2KIU7;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Radial spoke head protein 9 homolog;
GN   Name=RSPH9;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the axonemal radial spoke head which plays an
CC       important role in ciliary motility (By similarity). Essential for both
CC       the radial spoke head assembly and the central pair microtubule
CC       stability in ependymal motile cilia (By similarity). Required for
CC       motility of olfactory and neural cilia and for the structural integrity
CC       of ciliary axonemes in both 9+0 and 9+2 motile cilia (By similarity).
CC       {ECO:0000250|UniProtKB:Q5TYW6, ECO:0000250|UniProtKB:Q9D9V4}.
CC   -!- SUBUNIT: Interacts with RSPH6A. {ECO:0000250|UniProtKB:Q9D9V4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000305}. Cell projection, cilium, flagellum
CC       {ECO:0000250|UniProtKB:Q9D9V4}. Cell projection, kinocilium
CC       {ECO:0000250|UniProtKB:Q5TYW6}. Note=Radial spoke. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the flagellar radial spoke RSP9 family.
CC       {ECO:0000305}.
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DR   EMBL; BC112503; AAI12504.1; -; mRNA.
DR   RefSeq; NP_001039732.1; NM_001046267.1.
DR   AlphaFoldDB; Q2KIU7; -.
DR   SMR; Q2KIU7; -.
DR   STRING; 9913.ENSBTAP00000012563; -.
DR   PaxDb; Q2KIU7; -.
DR   PRIDE; Q2KIU7; -.
DR   Ensembl; ENSBTAT00000012563; ENSBTAP00000012563; ENSBTAG00000009549.
DR   GeneID; 523327; -.
DR   KEGG; bta:523327; -.
DR   CTD; 221421; -.
DR   VEuPathDB; HostDB:ENSBTAG00000009549; -.
DR   VGNC; VGNC:34187; RSPH9.
DR   eggNOG; ENOG502QR99; Eukaryota.
DR   GeneTree; ENSGT00390000018686; -.
DR   HOGENOM; CLU_068343_1_0_1; -.
DR   InParanoid; Q2KIU7; -.
DR   OMA; HGYIYIG; -.
DR   OrthoDB; 978175at2759; -.
DR   TreeFam; TF323644; -.
DR   Proteomes; UP000009136; Chromosome 23.
DR   Bgee; ENSBTAG00000009549; Expressed in spermatocyte and 105 other tissues.
DR   GO; GO:0097729; C:9+2 motile cilium; IEA:Ensembl.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0060091; C:kinocilium; IEA:UniProtKB-SubCell.
DR   GO; GO:1904158; P:axonemal central apparatus assembly; IEA:Ensembl.
DR   GO; GO:0035082; P:axoneme assembly; IBA:GO_Central.
DR   GO; GO:0060294; P:cilium movement involved in cell motility; IBA:GO_Central.
DR   GO; GO:0044458; P:motile cilium assembly; IBA:GO_Central.
DR   GO; GO:0062177; P:radial spoke assembly; IEA:Ensembl.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Cilium biogenesis/degradation; Cytoplasm;
KW   Cytoskeleton; Flagellum; Reference proteome.
FT   CHAIN           1..276
FT                   /note="Radial spoke head protein 9 homolog"
FT                   /id="PRO_0000265096"
SQ   SEQUENCE   276 AA;  31294 MW;  BACEE065190F3DDB CRC64;
     MDAESLLLAL ELASGSGQGL SPDRRASLLT SLMLVKRDYR FDRVLFWGRI LGLVADYYIA
     QGVSEDQLAP RKTLYSLNCM EWSLLPPATK EMETQTSVVK GRFMGDPSHE YEHTELQKVN
     EGEKVFEEEV VVQIKEETRL VSVIDQIDKA VAVIPRGALF KTPFGPINVN RTFEGLSLSE
     AKKLSSYFHF REPVELKNKT LLEKAELDPS LDFMDSLEHD IPKGSWSVQM ERGNALVVLR
     SLLWPGLTFY HAPRTKNYGY IYVGTGEKNL DLPFML