ID   RSPH9_XENTR             Reviewed;         277 AA.
AC   Q6DFN5;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Radial spoke head protein 9 homolog;
GN   Name=rsph9; ORFNames=TNeu080g17.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the axonemal radial spoke head which plays an
CC       important role in ciliary motility (By similarity). Essential for both
CC       the radial spoke head assembly and the central pair microtubule
CC       stability in ependymal motile cilia (By similarity). Required for
CC       motility of olfactory and neural cilia and for the structural integrity
CC       of ciliary axonemes in both 9+0 and 9+2 motile cilia (By similarity).
CC       {ECO:0000250|UniProtKB:Q5TYW6, ECO:0000250|UniProtKB:Q9D9V4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000305}. Cell projection, cilium, flagellum
CC       {ECO:0000250|UniProtKB:Q9D9V4}. Cell projection, kinocilium
CC       {ECO:0000250|UniProtKB:Q5TYW6}. Note=Radial spoke. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the flagellar radial spoke RSP9 family.
CC       {ECO:0000305}.
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DR   EMBL; CR760050; CAJ82450.1; -; mRNA.
DR   EMBL; BC076699; AAH76699.1; -; mRNA.
DR   RefSeq; NP_001005021.1; NM_001005021.1.
DR   AlphaFoldDB; Q6DFN5; -.
DR   SMR; Q6DFN5; -.
DR   STRING; 8364.ENSXETP00000023794; -.
DR   PaxDb; Q6DFN5; -.
DR   DNASU; 448532; -.
DR   GeneID; 448532; -.
DR   KEGG; xtr:448532; -.
DR   CTD; 221421; -.
DR   Xenbase; XB-GENE-5941075; rsph9.
DR   eggNOG; ENOG502QR99; Eukaryota.
DR   InParanoid; Q6DFN5; -.
DR   OrthoDB; 978175at2759; -.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000010879; Expressed in neurula embryo and 12 other tissues.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0060091; C:kinocilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0035082; P:axoneme assembly; IBA:GO_Central.
DR   GO; GO:0060294; P:cilium movement involved in cell motility; IBA:GO_Central.
DR   GO; GO:0044458; P:motile cilium assembly; IBA:GO_Central.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Cilium biogenesis/degradation; Cytoplasm;
KW   Cytoskeleton; Flagellum; Reference proteome.
FT   CHAIN           1..277
FT                   /note="Radial spoke head protein 9 homolog"
FT                   /id="PRO_0000359749"
SQ   SEQUENCE   277 AA;  30587 MW;  CCE4B4A8CC01413C CRC64;
     MDAETLSLSL ELVSGSGPGL SAEQCAALRA SLPLLHRDLR LRRLRLWGVV LGLRGDYVIA
     RGWGGPDLLR GQLSFYSLNC VDWCLLPPAT DAHIAQTQGI KGRFVGDPAH EYEYIVRNTA
     GGGDSALEEE LTTHIKEEVR LTGTIAMIDR EAAVAPRGAY IRNPLGQVIV NHSFRGLEVS
     EGKKLSSYFH FTPSLNPKKK SLLEKAALDP SIDFLDSLEH DIPRGSWSLQ LEQGDSVLIL
     RSLLWLGMTF YHVPLTPLHG HLYIGTGERN LDLPFMI