RSRC2_BOVIN
ID RSRC2_BOVIN Reviewed; 435 AA.
AC A6QLS2; A7E3S0;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 2.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Arginine/serine-rich coiled-coil protein 2;
GN Name=RSRC2;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=Hereford; TISSUE=Fetal skin;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=A6QLS2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=A6QLS2-2; Sequence=VSP_030439;
CC -!- SIMILARITY: Belongs to the RSRC2 family. {ECO:0000305}.
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DR EMBL; BT030691; ABS45007.1; -; mRNA.
DR EMBL; BC148066; AAI48067.1; -; mRNA.
DR RefSeq; NP_001095616.1; NM_001102146.1. [A6QLS2-2]
DR RefSeq; XP_005217927.1; XM_005217870.2. [A6QLS2-1]
DR AlphaFoldDB; A6QLS2; -.
DR STRING; 9913.ENSBTAP00000008042; -.
DR PaxDb; A6QLS2; -.
DR PRIDE; A6QLS2; -.
DR Ensembl; ENSBTAT00000008042; ENSBTAP00000008042; ENSBTAG00000006118. [A6QLS2-1]
DR Ensembl; ENSBTAT00000055724; ENSBTAP00000049555; ENSBTAG00000006118. [A6QLS2-1]
DR GeneID; 532701; -.
DR KEGG; bta:532701; -.
DR CTD; 65117; -.
DR VEuPathDB; HostDB:ENSBTAG00000006118; -.
DR eggNOG; ENOG502QQ3C; Eukaryota.
DR GeneTree; ENSGT00730000111142; -.
DR HOGENOM; CLU_051694_0_0_1; -.
DR InParanoid; A6QLS2; -.
DR OMA; LWANKSK; -.
DR OrthoDB; 1343985at2759; -.
DR TreeFam; TF325523; -.
DR Proteomes; UP000009136; Chromosome 17.
DR Bgee; ENSBTAG00000006118; Expressed in intramuscular adipose tissue and 108 other tissues.
DR ExpressionAtlas; A6QLS2; baseline and differential.
DR InterPro; IPR028124; SMAP_dom.
DR Pfam; PF15477; SMAP; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Alternative splicing; Coiled coil; Isopeptide bond;
KW Phosphoprotein; Reference proteome; Ubl conjugation.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT CHAIN 2..435
FT /note="Arginine/serine-rich coiled-coil protein 2"
FT /id="PRO_0000314936"
FT REGION 1..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 230..272
FT /evidence="ECO:0000255"
FT COMPBIAS 1..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..212
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 4
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 6
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 16
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 17
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 30
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 32
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 104
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 377
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT CROSSLNK 376
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO1); alternate"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT CROSSLNK 376
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2); alternate"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT VAR_SEQ 1..69
FT /note="MAASDTERDGLAPEKTSPDTDKKKEQSDVSVSPRASKHHYSRSRSRSRERKR
FT KSDNEGRKHRSRSRSKE -> MIRTNFFLKQ (in isoform 2)"
FT /evidence="ECO:0000303|Ref.2"
FT /id="VSP_030439"
SQ SEQUENCE 435 AA; 50578 MW; 151544CE5059BABF CRC64;
MAASDTERDG LAPEKTSPDT DKKKEQSDVS VSPRASKHHY SRSRSRSRER KRKSDNEGRK
HRSRSRSKEA RRHESKDKSS KKHKSEEHND KEHSSDKGRE RLNSSENGED RHKRKERKSS
RGRSHSRSRS RERRHRSRSR ERKKSRSRSR DRKKSRSRSR ERKKSRSRSR ERKRRIRSRS
RSRSRHRHRS RSRSRTRSRS RDRKKRIEKP RRFSRSLSRT PSPPPFRGRN TAMDAQEALA
RRLERAKKLQ EQREKEMVEK QKQQEIAAAA AATGGSVLNV AALLASGTQV TPQIAMAAQM
AALQAKALAE TGIAVPSYYN PAAVNPMKFA EQEKKRKMLW QGKKEGDKSQ SAEIWEKLNF
GNKDQNVKFR KLMGIKSEDE AGCSSVDEES YKTLKQQEEV FRNLDAQYEM ARSQTHTQRG
MGLGFTSSMR GMDTV
