RSRC2_DANRE
ID RSRC2_DANRE Reviewed; 407 AA.
AC Q6NWI1;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Arginine/serine-rich coiled-coil protein 2;
GN Name=rsrc2; ORFNames=si:ch211-110p13.2, zgc:85695;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
CC -!- SIMILARITY: Belongs to the RSRC2 family. {ECO:0000305}.
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DR EMBL; BC067581; AAH67581.1; -; mRNA.
DR EMBL; BX957226; CAM13132.1; -; Genomic_DNA.
DR RefSeq; NP_998445.1; NM_213280.1.
DR AlphaFoldDB; Q6NWI1; -.
DR STRING; 7955.ENSDARP00000062365; -.
DR PaxDb; Q6NWI1; -.
DR PRIDE; Q6NWI1; -.
DR Ensembl; ENSDART00000062366; ENSDARP00000062365; ENSDARG00000042534.
DR GeneID; 406566; -.
DR KEGG; dre:406566; -.
DR CTD; 65117; -.
DR ZFIN; ZDB-GENE-040426-2457; rsrc2.
DR eggNOG; ENOG502QQ3C; Eukaryota.
DR GeneTree; ENSGT00730000111142; -.
DR HOGENOM; CLU_051694_0_0_1; -.
DR InParanoid; Q6NWI1; -.
DR OrthoDB; 1361713at2759; -.
DR PhylomeDB; Q6NWI1; -.
DR TreeFam; TF325523; -.
DR PRO; PR:Q6NWI1; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 5.
DR Bgee; ENSDARG00000042534; Expressed in swim bladder and 27 other tissues.
DR ExpressionAtlas; Q6NWI1; baseline.
DR InterPro; IPR028124; SMAP_dom.
DR Pfam; PF15477; SMAP; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..407
FT /note="Arginine/serine-rich coiled-coil protein 2"
FT /id="PRO_0000314941"
FT REGION 1..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 191..221
FT /evidence="ECO:0000255"
FT COMPBIAS 28..58
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..175
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 46602 MW; C698A760DF0A265D CRC64;
MAANDAELHD SFSGKSQPGE NRKASRSSKH CSRSRSRSTE RKRKSGDKRH KRSHSRSKEA
RKKDSEKALK CQSGSEERLE FSDKGRDRLS EDTEERHRRK DKKTSRPRSH SRSRSKEKRH
HNRNWDKRRS RSRSRSRDKK RRARSRSNSR SKHRHRSRSR SKSREKKKRI EKSRKKSRSP
SISPVTFRGR NTAMDAQEAL ARRLERAKKL QEQKEKDMLE KWQHQEKAAA STPQCDPAAA
APSPALNVAA LLASGTQVTP QIAMAAQMAA LQAKTLAETG IAVPSYYNPS AVNPMKFAEQ
EKKRKMLWQG KKEGDNKSQT AELWEKLNFG NKDQNVKFRK LMGIKGEEEA ASSAAVNEDG
LKTLQQQEEM FRNLDVQYEM ARSQTHTQRG MGLGFSSSFS SRGMDAV