RSRC2_MOUSE
ID RSRC2_MOUSE Reviewed; 376 AA.
AC A2RTL5;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-MAR-2007, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Arginine/serine-rich coiled-coil protein 2;
GN Name=Rsrc2;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the RSRC2 family. {ECO:0000305}.
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DR EMBL; BC132550; AAI32551.1; -; mRNA.
DR EMBL; BC132552; AAI32553.1; -; mRNA.
DR CCDS; CCDS39272.1; -.
DR RefSeq; NP_001005525.1; NM_001005525.2.
DR RefSeq; NP_079714.1; NM_025438.2.
DR RefSeq; XP_006530309.1; XM_006530246.3.
DR RefSeq; XP_006530310.1; XM_006530247.3.
DR AlphaFoldDB; A2RTL5; -.
DR SMR; A2RTL5; -.
DR BioGRID; 228991; 5.
DR STRING; 10090.ENSMUSP00000138691; -.
DR EPD; A2RTL5; -.
DR MaxQB; A2RTL5; -.
DR PaxDb; A2RTL5; -.
DR PeptideAtlas; A2RTL5; -.
DR PRIDE; A2RTL5; -.
DR ProteomicsDB; 256791; -.
DR Antibodypedia; 31659; 118 antibodies from 20 providers.
DR DNASU; 208606; -.
DR Ensembl; ENSMUST00000050827; ENSMUSP00000050563; ENSMUSG00000029422.
DR Ensembl; ENSMUST00000057795; ENSMUSP00000049942; ENSMUSG00000029422.
DR GeneID; 208606; -.
DR KEGG; mmu:208606; -.
DR UCSC; uc008zoi.2; mouse.
DR CTD; 65117; -.
DR MGI; MGI:1913489; Rsrc2.
DR VEuPathDB; HostDB:ENSMUSG00000029422; -.
DR eggNOG; ENOG502QQ3C; Eukaryota.
DR GeneTree; ENSGT00730000111142; -.
DR HOGENOM; CLU_051694_0_0_1; -.
DR InParanoid; A2RTL5; -.
DR OrthoDB; 1343985at2759; -.
DR PhylomeDB; A2RTL5; -.
DR BioGRID-ORCS; 208606; 5 hits in 25 CRISPR screens.
DR ChiTaRS; Rsrc2; mouse.
DR PRO; PR:A2RTL5; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; A2RTL5; protein.
DR Bgee; ENSMUSG00000029422; Expressed in undifferentiated genital tubercle and 255 other tissues.
DR ExpressionAtlas; A2RTL5; baseline and differential.
DR Genevisible; A2RTL5; MM.
DR InterPro; IPR028124; SMAP_dom.
DR Pfam; PF15477; SMAP; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Isopeptide bond; Phosphoprotein; Reference proteome;
KW Ubl conjugation.
FT CHAIN 1..376
FT /note="Arginine/serine-rich coiled-coil protein 2"
FT /id="PRO_0000314938"
FT REGION 1..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 171..214
FT /evidence="ECO:0000255"
FT COMPBIAS 8..56
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..153
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 45
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT MOD_RES 318
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT CROSSLNK 317
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO1); alternate"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
FT CROSSLNK 317
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2); alternate"
FT /evidence="ECO:0000250|UniProtKB:Q7L4I2"
SQ SEQUENCE 376 AA; 43876 MW; B1C12DB396B73B11 CRC64;
MIRTNFLLKQ GRRHESKDKS SKRHKSEEHN DKEHSSDKGR ERLNSSENGE DRHKRKERKS
SRGRSHSRSR SRERRHRSRS RERKKSRSRS RDRKKSRSRS RDRKKSRSRS RDRKRRIRTR
SRSRSRHRHR TRSRSRSRSR SRDRKKRIEK PRRFSRSLSR TPSPPPFRGR NTAMDAQEAL
ARRLERAKKL QEQREKEMVE KQKQQEMAAA AAATGGSVLN VAALLASGTQ VTPQIAMAAQ
MAALQAKALA ETGIAVPSYY NPAAVNPMKF AEQEKKRKML WQGKKEGDKS QSAEIWEKLN
FGNKDQNVKF RKLMGIKSED EAGCSSVDEE SYKTLKQQEE VFRNLDAQYE MARSQTHTQR
GMGLGFTSSM RGMDTV