ID   ABCF2_BOVIN             Reviewed;         625 AA.
AC   Q2KJA2; Q1JPK5;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=ATP-binding cassette sub-family F member 2;
GN   Name=ABCF2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC       EF3 subfamily. {ECO:0000305}.
CC   -!- CAUTION: Lacks transmembrane domains and is probably not involved in
CC       transport. {ECO:0000305}.
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DR   EMBL; BT025348; ABF57304.1; -; mRNA.
DR   EMBL; BC105443; AAI05444.1; -; mRNA.
DR   RefSeq; NP_001039601.1; NM_001046136.2.
DR   RefSeq; XP_005205889.1; XM_005205832.3.
DR   AlphaFoldDB; Q2KJA2; -.
DR   SMR; Q2KJA2; -.
DR   STRING; 9913.ENSBTAP00000000799; -.
DR   PaxDb; Q2KJA2; -.
DR   PRIDE; Q2KJA2; -.
DR   Ensembl; ENSBTAT00000000799; ENSBTAP00000000799; ENSBTAG00000000607.
DR   Ensembl; ENSBTAT00000068255; ENSBTAP00000068739; ENSBTAG00000000607.
DR   Ensembl; ENSBTAT00000073665; ENSBTAP00000065368; ENSBTAG00000000607.
DR   GeneID; 513061; -.
DR   KEGG; bta:513061; -.
DR   CTD; 10061; -.
DR   VEuPathDB; HostDB:ENSBTAG00000000607; -.
DR   VGNC; VGNC:25481; ABCF2.
DR   eggNOG; KOG0927; Eukaryota.
DR   GeneTree; ENSGT00630000089910; -.
DR   HOGENOM; CLU_000604_36_6_1; -.
DR   InParanoid; Q2KJA2; -.
DR   OMA; DKMFLDN; -.
DR   OrthoDB; 580544at2759; -.
DR   TreeFam; TF105208; -.
DR   Proteomes; UP000009136; Chromosome 4.
DR   Bgee; ENSBTAG00000000607; Expressed in spermatid and 106 other tissues.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032781; ABC_tran_Xtn.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF12848; ABC_tran_Xtn; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   2: Evidence at transcript level;
KW   Acetylation; ATP-binding; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Repeat.
FT   CHAIN           1..625
FT                   /note="ATP-binding cassette sub-family F member 2"
FT                   /id="PRO_0000238917"
FT   DOMAIN          88..327
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          398..615
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..54
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         120..127
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         432..439
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   MOD_RES         220
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UG63"
FT   MOD_RES         306
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UG63"
FT   MOD_RES         514
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UG63"
SQ   SEQUENCE   625 AA;  71475 MW;  88ECBE4A6308A232 CRC64;
     MPSDLAKKKA AKKKEAAKAR QRPRKGHEEN GDAITEPQVA EERNEEANGR ETTEVDLLTK
     ELEDFEMKKA AARAVTGVLA SHPNSTDAHI INLSLTFHGQ ELLSDTKLEL NSGRRYGLIG
     LNGIGKSMLL SAIGKREVPI PEHIDIYHLT REMPPSDKTP LQCVMEVDTE RAMLEREAER
     LAHEDAECEK LLELYERLEE LDADKAEMRA SRILHGLGFT PAMQRKKLKD FSGGWRMRVA
     LARALFIRPF MLLLDEPTNH LDLDACVWLE EELKTFKRIL VLVSHSQDFL NGVCTNIIHM
     HNKKLKYYTG NYDQYVKTRL ELEENQMKRF HWEQDQIAHM KNYIARFGHG SAKLARQAQS
     KEKTLQKMMA SGLTERVVSD KTLSFYFPPC GKIPPPVIMV QNVSFKYTKD GPCIYNNLEF
     GIDLDTRVAL VGPNGAGKST LLKLLTGELL PTDGMIRKHS HVKIGRYHQH LQEQLDLDLS
     PLEYMMKCYP EIKEKEEMRK IIGRYGLTGK QQVSPIRNLS DGQKCRVCLA WLAWQNPHML
     FLDEPTNHLD IETIDALADA INDFEGGMML VSHDFRLIQQ VAQEIWVCEK QTITKWPGDI
     LAYKEHLKSK LVGEEPQPTR RTHNV