RSSA_CAEEL
ID RSSA_CAEEL Reviewed; 276 AA.
AC P46769;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 157.
DE RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03015};
GN Name=rps-0 {ECO:0000255|HAMAP-Rule:MF_03015}; ORFNames=B0393.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP PROTEIN SEQUENCE OF 2-17; 42-52; 64-80; 129-155; 170-180 AND 192-200,
RP IDENTIFICATION BY MASS SPECTROMETRY, AND ACETYLATION AT SER-2.
RA Bienvenut W.V.;
RL Submitted (AUG-2005) to UniProtKB.
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND DEVELOPMENTAL STAGE.
RX PubMed=15996007; DOI=10.1002/pmic.200401154;
RA Tabuse Y., Nabetani T., Tsugita A.;
RT "Proteomic analysis of protein expression profiles during Caenorhabditis
RT elegans development using two-dimensional difference gel electrophoresis.";
RL Proteomics 5:2876-2891(2005).
CC -!- FUNCTION: Required for the assembly and/or stability of the 40S
CC ribosomal subunit. Required for the processing of the 20S rRNA-
CC precursor to mature 18S rRNA in a late step of the maturation of 40S
CC ribosomal subunits. {ECO:0000255|HAMAP-Rule:MF_03015}.
CC -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC contains about 33 different proteins and 1 molecule of RNA (18S). The
CC 60S subunit contains about 49 different proteins and 3 molecules of RNA
CC (28S, 5.8S and 5S). Interacts with rps-21. {ECO:0000255|HAMAP-
CC Rule:MF_03015}.
CC -!- INTERACTION:
CC P46769; P49197: rps-21; NbExp=4; IntAct=EBI-313262, EBI-313268;
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- DEVELOPMENTAL STAGE: Expressed at a stable level throughout
CC development. {ECO:0000269|PubMed:15996007}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS2 family.
CC {ECO:0000255|HAMAP-Rule:MF_03015}.
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DR EMBL; Z37983; CAA86061.1; -; Genomic_DNA.
DR PIR; T18742; T18742.
DR RefSeq; NP_497978.1; NM_065577.5.
DR AlphaFoldDB; P46769; -.
DR SMR; P46769; -.
DR BioGRID; 40862; 100.
DR DIP; DIP-26217N; -.
DR IntAct; P46769; 4.
DR STRING; 6239.B0393.1.1; -.
DR iPTMnet; P46769; -.
DR World-2DPAGE; 0020:P46769; -.
DR EPD; P46769; -.
DR PaxDb; P46769; -.
DR PeptideAtlas; P46769; -.
DR EnsemblMetazoa; B0393.1.1; B0393.1.1; WBGene00004469.
DR GeneID; 175628; -.
DR KEGG; cel:CELE_B0393.1; -.
DR UCSC; B0393.1.1; c. elegans.
DR CTD; 175628; -.
DR WormBase; B0393.1; CE00854; WBGene00004469; rps-0.
DR eggNOG; KOG0830; Eukaryota.
DR GeneTree; ENSGT00950000183099; -.
DR HOGENOM; CLU_058171_1_0_1; -.
DR InParanoid; P46769; -.
DR OMA; QQKTKDM; -.
DR OrthoDB; 1129610at2759; -.
DR PhylomeDB; P46769; -.
DR Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-CEL-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR Reactome; R-CEL-72702; Ribosomal scanning and start codon recognition.
DR Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:P46769; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00004469; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd01425; RPS2; 1.
DR HAMAP; MF_03015; Ribosomal_S2_euk; 1.
DR InterPro; IPR001865; Ribosomal_S2.
DR InterPro; IPR018130; Ribosomal_S2_CS.
DR InterPro; IPR027498; Ribosomal_S2_euk.
DR InterPro; IPR005707; Ribosomal_S2_euk/arc.
DR InterPro; IPR023591; Ribosomal_S2_flav_dom_sf.
DR PANTHER; PTHR11489; PTHR11489; 1.
DR Pfam; PF00318; Ribosomal_S2; 1.
DR PRINTS; PR00395; RIBOSOMALS2.
DR SUPFAM; SSF52313; SSF52313; 1.
DR TIGRFAMs; TIGR01012; uS2_euk_arch; 1.
DR PROSITE; PS00962; RIBOSOMAL_S2_1; 1.
DR PROSITE; PS00963; RIBOSOMAL_S2_2; 1.
PE 1: Evidence at protein level;
KW Acetylation; Cytoplasm; Direct protein sequencing; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03015,
FT ECO:0000269|Ref.2"
FT CHAIN 2..276
FT /note="40S ribosomal protein SA"
FT /id="PRO_0000134352"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03015,
FT ECO:0000269|Ref.2"
SQ SEQUENCE 276 AA; 30703 MW; 51CB51C5C1B923DE CRC64;
MSGGAAHSAL TEEDVMKLLA TQAHLGSTNL NFQMQQYVYK RRFDGPNIIN VKKTWEKLLL
AARAIAAVEN PADVVVVSAR PYAQRALLKF AAHTGATAIF GRFSPGCLTN QIQKTFKEPR
LLVISDPRID HQAVTEASYV GVPVISFVNT ESPLKLIDIG VPCNNKGERS IGLMWWMLAR
EILILRGKIS RQTGFVLEGK EIMPDLYFYR DPTETEKEET GAHADVAEAQ EYQQPTDIDF
TTQGGKVDDW AAETATWTAE TKTTEEWANA PTQSNW
