ID   RSSA_DROSI              Reviewed;         270 AA.
AC   Q0H6L1;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03015};
DE   AltName: Full=Protein stubarista {ECO:0000255|HAMAP-Rule:MF_03015};
GN   Name=sta {ECO:0000255|HAMAP-Rule:MF_03015};
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16547109; DOI=10.1534/genetics.105.054346;
RA   Ko W.-Y., Piao S., Akashi H.;
RT   "Strong regional heterogeneity in base composition evolution on the
RT   Drosophila X chromosome.";
RL   Genetics 174:349-362(2006).
CC   -!- FUNCTION: Required for the assembly and/or stability of the 40S
CC       ribosomal subunit. Required for the processing of the 20S rRNA-
CC       precursor to mature 18S rRNA in a late step of the maturation of 40S
CC       ribosomal subunits. Required during oogenesis and imaginal development.
CC       {ECO:0000255|HAMAP-Rule:MF_03015}.
CC   -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC       consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC       contains about 33 different proteins and 1 molecule of RNA (18S). The
CC       60S subunit contains about 49 different proteins and 3 molecules of RNA
CC       (28S, 5.8S and 5S). Interacts with oho23B/rpS21. {ECO:0000255|HAMAP-
CC       Rule:MF_03015}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03015}.
CC       Nucleus {ECO:0000255|HAMAP-Rule:MF_03015}. Note=May associate with
CC       nascent RNP complexes within the nucleus. {ECO:0000255|HAMAP-
CC       Rule:MF_03015}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS2 family.
CC       {ECO:0000255|HAMAP-Rule:MF_03015}.
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DR   EMBL; DQ185016; ABB00655.1; -; Genomic_DNA.
DR   RefSeq; XP_016037676.1; XM_016173143.1.
DR   AlphaFoldDB; Q0H6L1; -.
DR   SMR; Q0H6L1; -.
DR   EnsemblMetazoa; FBtr0355158; FBpp0319454; FBgn0029243.
DR   GeneID; 6724869; -.
DR   ChiTaRS; sta; fly.
DR   Bgee; FBgn0029243; Expressed in embryo and 3 other tissues.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0043022; F:ribosome binding; IEA:EnsemblMetazoa.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:UniProtKB-UniRule.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd01425; RPS2; 1.
DR   HAMAP; MF_03015; Ribosomal_S2_euk; 1.
DR   InterPro; IPR032281; 40S_SA_C.
DR   InterPro; IPR001865; Ribosomal_S2.
DR   InterPro; IPR018130; Ribosomal_S2_CS.
DR   InterPro; IPR027498; Ribosomal_S2_euk.
DR   InterPro; IPR005707; Ribosomal_S2_euk/arc.
DR   InterPro; IPR023591; Ribosomal_S2_flav_dom_sf.
DR   PANTHER; PTHR11489; PTHR11489; 1.
DR   Pfam; PF16122; 40S_SA_C; 1.
DR   Pfam; PF00318; Ribosomal_S2; 2.
DR   PRINTS; PR00395; RIBOSOMALS2.
DR   SUPFAM; SSF52313; SSF52313; 1.
DR   TIGRFAMs; TIGR01012; uS2_euk_arch; 1.
DR   PROSITE; PS00962; RIBOSOMAL_S2_1; 1.
DR   PROSITE; PS00963; RIBOSOMAL_S2_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Developmental protein; Nucleus; Ribonucleoprotein;
KW   Ribosomal protein.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_03015"
FT   CHAIN           2..270
FT                   /note="40S ribosomal protein SA"
FT                   /id="PRO_0000371587"
FT   REGION          214..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          251..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   270 AA;  30228 MW;  FEC452C3F1712C82 CRC64;
     MSGGLDILSL KEDDITKMLV ATTHLGSENV NFQMEQYVYK RRADGVNILN LGKTWEKLQL
     AARAIVAIDN PSDIFVISSR PIGQRAVLKF AKYTDTTPIA GRFTPGAFTN QIQPAFREPR
     LLVVTDPNTD HQPIMEASYV NIPVIAFTNT DSPLRYIDIA IPCNNKSAHS IGLMWWLLAR
     EVLRLRGTIS RSVEWPVVVD LFFYRDPEEA EKEEAAAKEL LPPPKIEEAV DHPVEETTNW
     ADEVAAETVG GVEDWNEDTV KTSWGSDGQF