RSSA_KLULA
ID RSSA_KLULA Reviewed; 254 AA.
AC Q6CN12;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=40S ribosomal protein S0 {ECO:0000255|HAMAP-Rule:MF_03015};
GN Name=RPS0 {ECO:0000255|HAMAP-Rule:MF_03015};
GN OrderedLocusNames=KLLA0E16171g;
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Required for the assembly and/or stability of the 40S
CC ribosomal subunit. Required for the processing of the 20S rRNA-
CC precursor to mature 18S rRNA in a late step of the maturation of 40S
CC ribosomal subunits. {ECO:0000255|HAMAP-Rule:MF_03015}.
CC -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC contains about 33 different proteins and 1 molecule of RNA (18S). The
CC 60S subunit contains about 49 different proteins and 3 molecules of RNA
CC (25S, 5.8S and 5S). Interacts with RPS21. {ECO:0000255|HAMAP-
CC Rule:MF_03015}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03015}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS2 family.
CC {ECO:0000255|HAMAP-Rule:MF_03015}.
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DR EMBL; CR382125; CAG99764.1; -; Genomic_DNA.
DR RefSeq; XP_454677.1; XM_454677.1.
DR PDB; 3J80; EM; 3.75 A; A=1-254.
DR PDB; 3J81; EM; 4.00 A; A=1-254.
DR PDB; 3JAM; EM; 3.46 A; A=1-254.
DR PDB; 3JAP; EM; 4.90 A; A=1-254.
DR PDB; 3JAQ; EM; 6.00 A; A=1-254.
DR PDB; 5IT7; EM; 3.60 A; A=2-207.
DR PDB; 5IT9; EM; 3.80 A; A=2-207.
DR PDB; 6FYX; EM; 3.05 A; A=1-254.
DR PDB; 6FYY; EM; 3.05 A; A=1-254.
DR PDB; 6GSM; EM; 5.15 A; A=2-209.
DR PDB; 6GSN; EM; 5.75 A; A=2-220.
DR PDB; 6UZ7; EM; 3.60 A; A=1-254.
DR PDBsum; 3J80; -.
DR PDBsum; 3J81; -.
DR PDBsum; 3JAM; -.
DR PDBsum; 3JAP; -.
DR PDBsum; 3JAQ; -.
DR PDBsum; 5IT7; -.
DR PDBsum; 5IT9; -.
DR PDBsum; 6FYX; -.
DR PDBsum; 6FYY; -.
DR PDBsum; 6GSM; -.
DR PDBsum; 6GSN; -.
DR PDBsum; 6UZ7; -.
DR AlphaFoldDB; Q6CN12; -.
DR SMR; Q6CN12; -.
DR STRING; 28985.XP_454677.1; -.
DR PRIDE; Q6CN12; -.
DR EnsemblFungi; CAG99764; CAG99764; KLLA0_E16171g.
DR GeneID; 2893732; -.
DR KEGG; kla:KLLA0_E16171g; -.
DR eggNOG; KOG0830; Eukaryota.
DR HOGENOM; CLU_058171_2_0_1; -.
DR InParanoid; Q6CN12; -.
DR OMA; ENKMKRY; -.
DR Proteomes; UP000000598; Chromosome E.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:UniProtKB-UniRule.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd01425; RPS2; 1.
DR HAMAP; MF_03015; Ribosomal_S2_euk; 1.
DR InterPro; IPR001865; Ribosomal_S2.
DR InterPro; IPR018130; Ribosomal_S2_CS.
DR InterPro; IPR027498; Ribosomal_S2_euk.
DR InterPro; IPR005707; Ribosomal_S2_euk/arc.
DR InterPro; IPR023591; Ribosomal_S2_flav_dom_sf.
DR PANTHER; PTHR11489; PTHR11489; 1.
DR Pfam; PF00318; Ribosomal_S2; 2.
DR PRINTS; PR00395; RIBOSOMALS2.
DR SUPFAM; SSF52313; SSF52313; 1.
DR TIGRFAMs; TIGR01012; uS2_euk_arch; 1.
DR PROSITE; PS00962; RIBOSOMAL_S2_1; 1.
DR PROSITE; PS00963; RIBOSOMAL_S2_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Cytoplasm; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03015"
FT CHAIN 2..254
FT /note="40S ribosomal protein S0"
FT /id="PRO_0000371634"
FT REGION 212..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..254
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03015"
FT HELIX 11..20
FT /evidence="ECO:0007829|PDB:3JAM"
FT TURN 21..24
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 37..40
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 46..48
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 50..66
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 67..69
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 70..72
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 73..77
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 80..92
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 96..100
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 104..108
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 119..124
FT /evidence="ECO:0007829|PDB:3JAM"
FT TURN 126..128
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 130..137
FT /evidence="ECO:0007829|PDB:3JAM"
FT TURN 138..140
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 143..145
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 157..159
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 168..185
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 187..189
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 191..193
FT /evidence="ECO:0007829|PDB:3JAM"
SQ SEQUENCE 254 AA; 28238 MW; BF62481CC047E9CC CRC64;
MSLPSTFDLT SEDAQLLLAA RVHLGAKNVQ VHQEPYVYKA RPDGVNVINV GKTWEKIVLA
ARIIAAIPNP EDVVAISSRT YGQRAVLKYA AHTGATPIAG RFTPGSFTNY ITRSFKEPRL
VIVTDPRSDA QAIKESSYVN IPVIALTDLD SPSEYVDVAI PCNNRGKHSI GLIWYLLARE
VLRLRGALPD RTQPWAIMPD LYFYRNPEEI EQQTAEEEAV ASGEQTEEAV DATEEQTEAA
EWAEEGQAQE EEWN
