ID   RSSA_LEIMA              Reviewed;         246 AA.
AC   Q4Q0Q0;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03015};
GN   ORFNames=LmjF36.5010, LmjF_36_5010;
GN   and
GN   ORFNames=LmjF36.5120, LmjF_36_5120;
OS   Leishmania major.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX   NCBI_TaxID=5664;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHOM/IL/81/Friedlin;
RX   PubMed=16020728; DOI=10.1126/science.1112680;
RA   Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G.,
RA   Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A.,
RA   Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M.,
RA   Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E.,
RA   Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M.,
RA   De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N.,
RA   Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A.,
RA   Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S.,
RA   Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M.,
RA   Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S.,
RA   Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M.,
RA   Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E.,
RA   Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C.,
RA   Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K.,
RA   Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V.,
RA   Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J.,
RA   Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D.,
RA   Barrell B.G., Myler P.J.;
RT   "The genome of the kinetoplastid parasite, Leishmania major.";
RL   Science 309:436-442(2005).
CC   -!- FUNCTION: Required for the assembly and/or stability of the 40S
CC       ribosomal subunit. Required for the processing of the 20S rRNA-
CC       precursor to mature 18S rRNA in a late step of the maturation of 40S
CC       ribosomal subunits. {ECO:0000255|HAMAP-Rule:MF_03015}.
CC   -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC       consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC       contains about 33 different proteins and 1 molecule of RNA (18S). The
CC       60S subunit contains about 49 different proteins and 3 molecules of RNA
CC       (25S, 5.8S and 5S). Interacts with ribosomal protein S21.
CC       {ECO:0000255|HAMAP-Rule:MF_03015}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03015}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS2 family.
CC       {ECO:0000255|HAMAP-Rule:MF_03015}.
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DR   EMBL; FR796432; CAJ09473.1; -; Genomic_DNA.
DR   EMBL; FR796432; CAJ09484.1; -; Genomic_DNA.
DR   RefSeq; XP_001687087.1; XM_001687035.1.
DR   RefSeq; XP_001687098.1; XM_001687046.1.
DR   AlphaFoldDB; Q4Q0Q0; -.
DR   SMR; Q4Q0Q0; -.
DR   STRING; 5664.LmjF.36.5010; -.
DR   EnsemblProtists; CAJ09473; CAJ09473; LMJF_36_5010.
DR   EnsemblProtists; CAJ09484; CAJ09484; LMJF_36_5120.
DR   GeneID; 5655803; -.
DR   GeneID; 5655814; -.
DR   KEGG; lma:LMJF_36_5010; -.
DR   KEGG; lma:LMJF_36_5120; -.
DR   VEuPathDB; TriTrypDB:LmjF.36.5010; -.
DR   VEuPathDB; TriTrypDB:LMJLV39_360062100; -.
DR   VEuPathDB; TriTrypDB:LMJSD75_360061800; -.
DR   eggNOG; KOG0830; Eukaryota.
DR   InParanoid; Q4Q0Q0; -.
DR   OMA; ENKMKRY; -.
DR   Proteomes; UP000000542; Chromosome 36.
DR   GO; GO:0005737; C:cytoplasm; ISO:GeneDB.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd01425; RPS2; 1.
DR   HAMAP; MF_03015; Ribosomal_S2_euk; 1.
DR   InterPro; IPR001865; Ribosomal_S2.
DR   InterPro; IPR018130; Ribosomal_S2_CS.
DR   InterPro; IPR027498; Ribosomal_S2_euk.
DR   InterPro; IPR005707; Ribosomal_S2_euk/arc.
DR   InterPro; IPR023591; Ribosomal_S2_flav_dom_sf.
DR   PANTHER; PTHR11489; PTHR11489; 1.
DR   Pfam; PF00318; Ribosomal_S2; 1.
DR   PRINTS; PR00395; RIBOSOMALS2.
DR   SUPFAM; SSF52313; SSF52313; 1.
DR   TIGRFAMs; TIGR01012; uS2_euk_arch; 1.
DR   PROSITE; PS00963; RIBOSOMAL_S2_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..246
FT                   /note="40S ribosomal protein SA"
FT                   /id="PRO_0000371616"
SQ   SEQUENCE   246 AA;  27500 MW;  38D91DD26DAB393D CRC64;
     MSAVESGSKV LRMKESDAQK LLAMRCHIGT RNQSSAMKKY IYGRTAEGSH IIDVHMMWEK
     LILAARVIAA VENPKDVCVC SSRLYGTRAI YKFSQHVGTS FHGGRFIPGT FTNQIQKKFV
     QPRVLVVTDP RTDHQAIREA SLVNIPVIAL CDTDAPLEYV DIAIPCNNRG IKSIGMMYWL
     LAREVLRLRG TIVRSVPWEE KVDLFFYRDP NEAAEEKAAA AAAAPAAEAE EGFGWVERND
     DNAWEA