RSSA_NEUCR
ID RSSA_NEUCR Reviewed; 290 AA.
AC Q01291; Q7RY13; Q8X068;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 30-APR-2003, sequence version 2.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=40S ribosomal protein S0 {ECO:0000255|HAMAP-Rule:MF_03015};
DE AltName: Full=Ribosome-associated protein 1;
GN Name=rps-0 {ECO:0000255|HAMAP-Rule:MF_03015}; Synonyms=rap-1;
GN ORFNames=B19C19.040, NCU03393;
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8611592; DOI=10.1016/0005-2728(95)00144-1;
RA Melnik V.I., Bowman B.J.;
RT "Isolation of the vma-6 gene encoding a 41 kDa subunit of the Neurospora
RT crassa vacuolar ATPase, and an adjoining gene encoding a ribosome-
RT associated protein.";
RL Biochim. Biophys. Acta 1273:77-83(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12655011; DOI=10.1093/nar/gkg293;
RA Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D.,
RA Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
RT "What's in the genome of a filamentous fungus? Analysis of the Neurospora
RT genome sequence.";
RL Nucleic Acids Res. 31:1944-1954(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- FUNCTION: Required for the assembly and/or stability of the 40S
CC ribosomal subunit. Required for the processing of the 20S rRNA-
CC precursor to mature 18S rRNA in a late step of the maturation of 40S
CC ribosomal subunits. {ECO:0000255|HAMAP-Rule:MF_03015}.
CC -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC contains about 33 different proteins and 1 molecule of RNA (18S). The
CC 60S subunit contains about 49 different proteins and 3 molecules of RNA
CC (25S, 5.8S and 5S). Interacts with rps-21. {ECO:0000255|HAMAP-
CC Rule:MF_03015}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03015}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS2 family.
CC {ECO:0000255|HAMAP-Rule:MF_03015}.
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DR EMBL; U36470; AAB02772.1; -; Genomic_DNA.
DR EMBL; AL669992; CAD21142.1; -; Genomic_DNA.
DR EMBL; CM002237; EAA27604.1; -; Genomic_DNA.
DR PIR; T47199; T47199.
DR RefSeq; XP_956840.1; XM_951747.3.
DR PDB; 7R81; EM; 2.70 A; B2=1-290.
DR PDBsum; 7R81; -.
DR AlphaFoldDB; Q01291; -.
DR SMR; Q01291; -.
DR STRING; 5141.EFNCRP00000002664; -.
DR PRIDE; Q01291; -.
DR EnsemblFungi; EAA27604; EAA27604; NCU03393.
DR GeneID; 3872987; -.
DR KEGG; ncr:NCU03393; -.
DR VEuPathDB; FungiDB:NCU03393; -.
DR HOGENOM; CLU_058171_0_1_1; -.
DR InParanoid; Q01291; -.
DR OMA; QCHLGAK; -.
DR Proteomes; UP000001805; Chromosome 6, Linkage Group II.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd01425; RPS2; 1.
DR HAMAP; MF_03015; Ribosomal_S2_euk; 1.
DR InterPro; IPR001865; Ribosomal_S2.
DR InterPro; IPR018130; Ribosomal_S2_CS.
DR InterPro; IPR027498; Ribosomal_S2_euk.
DR InterPro; IPR005707; Ribosomal_S2_euk/arc.
DR InterPro; IPR023591; Ribosomal_S2_flav_dom_sf.
DR PANTHER; PTHR11489; PTHR11489; 1.
DR Pfam; PF00318; Ribosomal_S2; 2.
DR PRINTS; PR00395; RIBOSOMALS2.
DR SUPFAM; SSF52313; SSF52313; 1.
DR TIGRFAMs; TIGR01012; uS2_euk_arch; 1.
DR PROSITE; PS00963; RIBOSOMAL_S2_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT CHAIN 1..290
FT /note="40S ribosomal protein S0"
FT /id="PRO_0000134366"
FT REGION 243..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 84
FT /note="Y -> I (in Ref. 1; AAB02772)"
FT /evidence="ECO:0000305"
FT CONFLICT 174
FT /note="G -> A (in Ref. 1; AAB02772)"
FT /evidence="ECO:0000305"
FT CONFLICT 286..290
FT /note="KESSW -> RSPAGKQL (in Ref. 1; AAB02772)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 290 AA; 31501 MW; EAEB3AAB49F33C08 CRC64;
MAPANLPSIF NATSTDIEQL LAAQCHIGSK NLGVHMQPYL WKTRADGVNI LNVGKTWEKI
VLAARIIAAI DNPADICVIS ARPYGQRAVL KFAAHTGAQA IAGRFTPGSF TNYITRSFKE
PRLIIVTDPR TDAQAIKEAS YVNIPVIALC DADSPTEYVD VAIPTNNKGR HAIGCVWWML
AREVLRLRGT IYNRETPWDV MVDLYFYRDP EAEAEEKVEE EKLPGVEEEG VAAIESGFPA
TGDWEAAPAG FPATGEWSDA APGAAAPNWD ATAPATTADW AATEAKESSW
