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ABCF2_DICDI
ID   ABCF2_DICDI             Reviewed;         593 AA.
AC   Q8T6B7; Q54Q58;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=ABC transporter F family member 2;
GN   Name=abcF2; ORFNames=DDB_G0284047;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND NOMENCLATURE.
RC   STRAIN=AX4;
RX   PubMed=12456012; DOI=10.1128/ec.1.4.643-652.2002;
RA   Anjard C., Loomis W.F.;
RT   "Evolutionary analyses of ABC transporters of Dictyostelium discoideum.";
RL   Eukaryot. Cell 1:643-652(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC       EF3 subfamily. {ECO:0000305}.
CC   -!- CAUTION: Lacks transmembrane domains and is probably not involved in
CC       transport. {ECO:0000305}.
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DR   EMBL; AF479254; AAL87692.1; -; Genomic_DNA.
DR   EMBL; AAFI02000063; EAL65364.1; -; Genomic_DNA.
DR   RefSeq; XP_638739.1; XM_633647.1.
DR   AlphaFoldDB; Q8T6B7; -.
DR   SMR; Q8T6B7; -.
DR   STRING; 44689.DDB0191228; -.
DR   PaxDb; Q8T6B7; -.
DR   EnsemblProtists; EAL65364; EAL65364; DDB_G0284047.
DR   GeneID; 8624409; -.
DR   KEGG; ddi:DDB_G0284047; -.
DR   dictyBase; DDB_G0284047; abcF2.
DR   eggNOG; KOG0927; Eukaryota.
DR   HOGENOM; CLU_000604_36_6_1; -.
DR   InParanoid; Q8T6B7; -.
DR   OMA; DWMGQWT; -.
DR   PhylomeDB; Q8T6B7; -.
DR   PRO; PR:Q8T6B7; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   GO; GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.
DR   GO; GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032781; ABC_tran_Xtn.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF12848; ABC_tran_Xtn; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Repeat.
FT   CHAIN           1..593
FT                   /note="ABC transporter F family member 2"
FT                   /id="PRO_0000365607"
FT   DOMAIN          53..294
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          364..583
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         85..92
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         399..406
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   593 AA;  66841 MW;  E3C3C76A1CB1FB5E CRC64;
     MAKKGGKNNK SKKEVTPPTS DVEDEVQDKF KEMRLNAFTA TGALASKESS RDVKIEQVTL
     TFHGKELLSD TTVEINFGRR YGLIGQNGCG KSTFFQCLAV RELPIPEHID IFHLSEEAHP
     SERTALQSVI DDAEKEVKRL EVLEERLLEE QGPESEELFD VYERLENLDP TTFVPRASEI
     LIGLGFTSQT MLKKTKDLSG GWRMRVSLAK ALFIKPTLLL LDEPTNHLDL GACVWLEDYL
     ANYDRSLIII SHSQDFLNAV CTNIIHMTQS KLKYYGGNYD NFVKTKAELE VNQMKAYHKQ
     QEEIAHIKSF IASCGTYSNL VRQGKSKQKI IDKMEEAGLV ERVQEDKIFN FSFPPCGELA
     PPIMHFDNVT FSYSGKEADV LYRNLDLAID LDSRIALVGP NGAGKSTLLK LMVGQISPTQ
     GFIKKHSHLK MARYHQHAHE VLDLTATPLD FVRSKFAHMN KDTEEWRREI GRFGVTGKAQ
     TEAIGCMSDG IKSRLIFCLM ALENPHLLLL DEPTNHLDME CIDSLALAIN SFPGGMILVS
     HDFRLISQVA KEIWVCDNKT ITKWAGDITS YKNHLKAQMR DLTKQGALAS LKK
 
 
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