ID   RSTR_VIBCH              Reviewed;         112 AA.
AC   O34419;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Cryptic phage CTXphi transcriptional repressor RstR;
GN   Name=rstR1; OrderedLocusNames=VC_1455;
GN   and
GN   Name=rstR2; OrderedLocusNames=VC_1464;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 55056 / El Tor Ogawa E7946;
RX   PubMed=9220000; DOI=10.1046/j.1365-2958.1997.3911758.x;
RA   Waldor M.K., Rubin E.J., Pearson G.D., Kimsey H., Mekalanos J.J.;
RT   "Regulation, replication, and integration functions of the Vibrio cholerae
RT   CTXphi are encoded by region RS2.";
RL   Mol. Microbiol. 24:917-926(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Transcriptional repressor of the integrated CTXPhi phage gene
CC       rstA2.
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DR   EMBL; U83796; AAB81728.1; -; Genomic_DNA.
DR   EMBL; U83795; AAB81724.1; -; Genomic_DNA.
DR   EMBL; AE003852; AAF94621.1; -; Genomic_DNA.
DR   EMBL; AE003852; AAF94612.1; -; Genomic_DNA.
DR   PIR; H82197; H82197.
DR   RefSeq; NP_231098.1; NC_002505.1.
DR   RefSeq; NP_231107.1; NC_002505.1.
DR   RefSeq; WP_000693566.1; NZ_LT906614.1.
DR   AlphaFoldDB; O34419; -.
DR   SMR; O34419; -.
DR   STRING; 243277.VC_1455; -.
DR   DNASU; 2613961; -.
DR   EnsemblBacteria; AAF94612; AAF94612; VC_1455.
DR   EnsemblBacteria; AAF94621; AAF94621; VC_1464.
DR   GeneID; 57740127; -.
DR   KEGG; vch:VC_1455; -.
DR   KEGG; vch:VC_1464; -.
DR   eggNOG; COG1476; Bacteria.
DR   HOGENOM; CLU_066192_4_7_6; -.
DR   OMA; RWATDEN; -.
DR   BioCyc; VCHO:VC1464-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..112
FT                   /note="Cryptic phage CTXphi transcriptional repressor RstR"
FT                   /id="PRO_0000149735"
FT   DOMAIN          7..61
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   112 AA;  12746 MW;  77748953D6E7A0F0 CRC64;
     MKIKERLANQ RKAINKTQAQ MADEIGISLT SYKKYESGEG LPTMENLVKI ADALEISIDE
     LCGRWATDEN QELMLRLKKI QQLDEEEQKA ISMVLESMLI RHSTKSILNH GA