ID   RSTR_VIBCL              Reviewed;         111 AA.
AC   O85264;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Cryptic phage CTXphi transcriptional repressor RstR;
GN   Name=rstR;
OS   Vibrio cholerae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=666;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 25870 / Classical Inaba 569B / Serotype O1;
RX   PubMed=9618534; DOI=10.1073/pnas.95.12.7035;
RA   Kimsey H.H., Waldor M.K.;
RT   "CTXphi immunity: application in the development of cholera vaccines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 95:7035-7039(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=El Tor 86015 / Serotype O1;
RA   Kan B., Liu Y.Q., Qi G.M., Gao S.Y.;
RL   Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional repressor of the integrated CTXPhi phage gene
CC       rstA2.
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DR   EMBL; AF055890; AAC24223.1; -; Genomic_DNA.
DR   EMBL; AF220606; AAF29541.1; -; Genomic_DNA.
DR   RefSeq; WP_000492997.1; NZ_WNZR01000142.1.
DR   AlphaFoldDB; O85264; -.
DR   SMR; O85264; -.
DR   OMA; KNTYLAY; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..111
FT                   /note="Cryptic phage CTXphi transcriptional repressor RstR"
FT                   /id="PRO_0000149736"
FT   DOMAIN          6..60
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        17..36
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   111 AA;  12800 MW;  663D93FE99D2A3D6 CRC64;
     MFSSKIRDLR VERDLNQEEV ANGIGVGKNT YLAYEKGTQS PKLETVEKLA KFYGVPIAEL
     VSDSETNIDE KLKSKIRMIE SLDEPEKESL FILMEALLMR SKSREIQKEF R