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BCL7A_DANRE
ID   BCL7A_DANRE             Reviewed;         201 AA.
AC   Q5XFY4; Q6TLE3;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=B-cell CLL/lymphoma 7 protein family member A;
GN   Name=bcl7a; ORFNames=zgc:92023;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   TISSUE=Kidney marrow;
RX   PubMed=15520368; DOI=10.1073/pnas.0407241101;
RA   Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y.,
RA   Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X.,
RA   Look A.T., Chen Z.;
RT   "Hematopoietic gene expression profile in zebrafish kidney marrow.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q5XFY4-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q5XFY4-2; Sequence=VSP_019274, VSP_019275;
CC   -!- SIMILARITY: Belongs to the BCL7 family. {ECO:0000305}.
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DR   EMBL; AY394963; AAQ94590.1; -; mRNA.
DR   EMBL; BC084687; AAH84687.1; -; mRNA.
DR   RefSeq; NP_997725.1; NM_212560.1. [Q5XFY4-2]
DR   AlphaFoldDB; Q5XFY4; -.
DR   STRING; 7955.ENSDARP00000114813; -.
DR   PaxDb; Q5XFY4; -.
DR   Ensembl; ENSDART00000190477; ENSDARP00000146672; ENSDARG00000052907. [Q5XFY4-2]
DR   Ensembl; ENSDART00000192289; ENSDARP00000154468; ENSDARG00000052907. [Q5XFY4-1]
DR   GeneID; 57952; -.
DR   KEGG; dre:57952; -.
DR   CTD; 605; -.
DR   ZFIN; ZDB-GENE-000607-16; bcl7a.
DR   eggNOG; KOG4095; Eukaryota.
DR   GeneTree; ENSGT00390000002172; -.
DR   InParanoid; Q5XFY4; -.
DR   OrthoDB; 1517597at2759; -.
DR   PhylomeDB; Q5XFY4; -.
DR   PRO; PR:Q5XFY4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 5.
DR   Bgee; ENSDARG00000052907; Expressed in gastrula and 22 other tissues.
DR   ExpressionAtlas; Q5XFY4; baseline and differential.
DR   InterPro; IPR006804; BCL7.
DR   PANTHER; PTHR12767; PTHR12767; 1.
DR   Pfam; PF04714; BCL_N; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..201
FT                   /note="B-cell CLL/lymphoma 7 protein family member A"
FT                   /id="PRO_0000239825"
FT   REGION          46..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..73
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..147
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        148..168
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..201
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         58
FT                   /note="D -> DK (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15520368"
FT                   /id="VSP_019274"
FT   VAR_SEQ         141..146
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15520368"
FT                   /id="VSP_019275"
SQ   SEQUENCE   201 AA;  22125 MW;  FECDE9D67035B66C CRC64;
     MSGRSVRAET RSRAKDDIKR VMAAIEKVRK WEKKWVTVGD TSLRIYKWVP VTEPKSDDNK
     NKKKGKDDKY GSEVTTPENS SSPGMMDMHD DNSNQSSIAD SSPLKQETSN NTSPAPEPMA
     ASQNDSSDLK NDQYPSKQPS SGQDHKSEQN HCSSESMTSK RDSKSQGDSE SFLDSSKSAQ
     ELEDGAPPSK KGKIDSSSEE S
 
 
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