BCL7A_DANRE
ID BCL7A_DANRE Reviewed; 201 AA.
AC Q5XFY4; Q6TLE3;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=B-cell CLL/lymphoma 7 protein family member A;
GN Name=bcl7a; ORFNames=zgc:92023;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Kidney marrow;
RX PubMed=15520368; DOI=10.1073/pnas.0407241101;
RA Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y.,
RA Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X.,
RA Look A.T., Chen Z.;
RT "Hematopoietic gene expression profile in zebrafish kidney marrow.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5XFY4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5XFY4-2; Sequence=VSP_019274, VSP_019275;
CC -!- SIMILARITY: Belongs to the BCL7 family. {ECO:0000305}.
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DR EMBL; AY394963; AAQ94590.1; -; mRNA.
DR EMBL; BC084687; AAH84687.1; -; mRNA.
DR RefSeq; NP_997725.1; NM_212560.1. [Q5XFY4-2]
DR AlphaFoldDB; Q5XFY4; -.
DR STRING; 7955.ENSDARP00000114813; -.
DR PaxDb; Q5XFY4; -.
DR Ensembl; ENSDART00000190477; ENSDARP00000146672; ENSDARG00000052907. [Q5XFY4-2]
DR Ensembl; ENSDART00000192289; ENSDARP00000154468; ENSDARG00000052907. [Q5XFY4-1]
DR GeneID; 57952; -.
DR KEGG; dre:57952; -.
DR CTD; 605; -.
DR ZFIN; ZDB-GENE-000607-16; bcl7a.
DR eggNOG; KOG4095; Eukaryota.
DR GeneTree; ENSGT00390000002172; -.
DR InParanoid; Q5XFY4; -.
DR OrthoDB; 1517597at2759; -.
DR PhylomeDB; Q5XFY4; -.
DR PRO; PR:Q5XFY4; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 5.
DR Bgee; ENSDARG00000052907; Expressed in gastrula and 22 other tissues.
DR ExpressionAtlas; Q5XFY4; baseline and differential.
DR InterPro; IPR006804; BCL7.
DR PANTHER; PTHR12767; PTHR12767; 1.
DR Pfam; PF04714; BCL_N; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..201
FT /note="B-cell CLL/lymphoma 7 protein family member A"
FT /id="PRO_0000239825"
FT REGION 46..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 58
FT /note="D -> DK (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15520368"
FT /id="VSP_019274"
FT VAR_SEQ 141..146
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15520368"
FT /id="VSP_019275"
SQ SEQUENCE 201 AA; 22125 MW; FECDE9D67035B66C CRC64;
MSGRSVRAET RSRAKDDIKR VMAAIEKVRK WEKKWVTVGD TSLRIYKWVP VTEPKSDDNK
NKKKGKDDKY GSEVTTPENS SSPGMMDMHD DNSNQSSIAD SSPLKQETSN NTSPAPEPMA
ASQNDSSDLK NDQYPSKQPS SGQDHKSEQN HCSSESMTSK RDSKSQGDSE SFLDSSKSAQ
ELEDGAPPSK KGKIDSSSEE S