ID   BCL7B_BOVIN             Reviewed;         202 AA.
AC   Q3T0A6;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=B-cell CLL/lymphoma 7 protein family member B;
GN   Name=BCL7B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Positive regulator of apoptosis. Plays a role in the Wnt
CC       signaling pathway, negatively regulating the expression of Wnt
CC       signaling components CTNNB1 and HMGA1. Involved in cell cycle
CC       progression, maintenance of the nuclear structure and stem cell
CC       differentiation. May play a role in lung tumor development or
CC       progression. {ECO:0000250|UniProtKB:Q921K9,
CC       ECO:0000250|UniProtKB:Q9BQE9}.
CC   -!- SIMILARITY: Belongs to the BCL7 family. {ECO:0000305}.
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DR   EMBL; BC102475; AAI02476.1; -; mRNA.
DR   RefSeq; NP_001029947.1; NM_001034775.2.
DR   AlphaFoldDB; Q3T0A6; -.
DR   STRING; 9913.ENSBTAP00000027371; -.
DR   PaxDb; Q3T0A6; -.
DR   PRIDE; Q3T0A6; -.
DR   Ensembl; ENSBTAT00000027371; ENSBTAP00000027371; ENSBTAG00000020544.
DR   GeneID; 615062; -.
DR   KEGG; bta:615062; -.
DR   CTD; 9275; -.
DR   VEuPathDB; HostDB:ENSBTAG00000020544; -.
DR   VGNC; VGNC:26450; BCL7B.
DR   eggNOG; KOG4095; Eukaryota.
DR   GeneTree; ENSGT00390000002172; -.
DR   HOGENOM; CLU_110835_1_0_1; -.
DR   InParanoid; Q3T0A6; -.
DR   OMA; VRKXKEK; -.
DR   OrthoDB; 1517597at2759; -.
DR   TreeFam; TF317441; -.
DR   Proteomes; UP000009136; Chromosome 25.
DR   Bgee; ENSBTAG00000020544; Expressed in trachea and 105 other tissues.
DR   GO; GO:0016514; C:SWI/SNF complex; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR006804; BCL7.
DR   PANTHER; PTHR12767; PTHR12767; 1.
DR   Pfam; PF04714; BCL_N; 1.
PE   2: Evidence at transcript level;
KW   Apoptosis; Differentiation; Phosphoprotein; Reference proteome;
KW   Wnt signaling pathway.
FT   CHAIN           1..202
FT                   /note="B-cell CLL/lymphoma 7 protein family member B"
FT                   /id="PRO_0000239828"
FT   REGION          53..202
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..138
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         114
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BQE9"
FT   MOD_RES         118
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BQE9"
FT   MOD_RES         120
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q921K9"
FT   MOD_RES         122
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BQE9"
FT   MOD_RES         127
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q921K9"
FT   MOD_RES         148
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q921K9"
FT   MOD_RES         152
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q921K9"
SQ   SEQUENCE   202 AA;  22197 MW;  1281370D686272C8 CRC64;
     MSGRSVRAET RSRAKDDIKK VMAAIEKVRK WEKKWVTVGD TSLRIFKWVP VTDSKEKEKS
     KSNSSAAREP NGFPSDASAN SSLLLEFQDE NSNQSSVSDV YQLKVDSSTN SSPSPQQSES
     LSPAHTSDFR TDDSQPPTLG QEILEEPSLP ASEVADEPPT LTKEEPVPLE TQIAEEEEDS
     SAPPLKRFCM DQPAVPQTAS ES