ID   RSZ21_ORYSJ             Reviewed;         185 AA.
AC   Q6K4N0; A0A0P0VQL4;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Serine/arginine-rich splicing factor RSZ21;
DE   AltName: Full=RS-containing zinc finger protein 21;
DE            Short=Os-RSZ21;
DE            Short=Os-RSZp21;
GN   Name=RSZP21; Synonyms=RSZP21B;
GN   OrderedLocusNames=Os02g0789400, LOC_Os02g54770;
GN   ORFNames=OJ1046_F07.9, OsJ_08668, OSJNBa0054K20.35;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   TISSUE SPECIFICITY, AND GENE FAMILY.
RX   PubMed=16339852; DOI=10.1105/tpc.105.037069;
RA   Isshiki M., Tsumoto A., Shimamoto K.;
RT   "The serine/arginine-rich protein family in rice plays important roles in
RT   constitutive and alternative splicing of pre-mRNA.";
RL   Plant Cell 18:146-158(2006).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=20884799; DOI=10.1105/tpc.110.078352;
RA   Barta A., Kalyna M., Reddy A.S.;
RT   "Implementing a rational and consistent nomenclature for serine/arginine-
RT   rich protein splicing factors (SR proteins) in plants.";
RL   Plant Cell 22:2926-2929(2010).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O81126}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, leaves and immature seeds.
CC       {ECO:0000269|PubMed:16339852}.
CC   -!- PTM: Extensively phosphorylated on serine residues in the RS domain.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the splicing factor SR family. {ECO:0000305}.
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DR   EMBL; AP003984; BAD19103.1; -; Genomic_DNA.
DR   EMBL; AP005535; BAD19873.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF10266.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS81304.1; -; Genomic_DNA.
DR   EMBL; CM000139; EEE57947.1; -; Genomic_DNA.
DR   EMBL; AK073210; BAG93345.1; -; mRNA.
DR   EMBL; AK073359; BAG93415.1; -; mRNA.
DR   RefSeq; XP_015622565.1; XM_015767079.1.
DR   RefSeq; XP_015622566.1; XM_015767080.1.
DR   RefSeq; XP_015622567.1; XM_015767081.1.
DR   AlphaFoldDB; Q6K4N0; -.
DR   SMR; Q6K4N0; -.
DR   STRING; 4530.OS02T0789400-01; -.
DR   PaxDb; Q6K4N0; -.
DR   PRIDE; Q6K4N0; -.
DR   EnsemblPlants; Os02t0789400-01; Os02t0789400-01; Os02g0789400.
DR   EnsemblPlants; Os02t0789400-02; Os02t0789400-02; Os02g0789400.
DR   GeneID; 4330968; -.
DR   Gramene; Os02t0789400-01; Os02t0789400-01; Os02g0789400.
DR   Gramene; Os02t0789400-02; Os02t0789400-02; Os02g0789400.
DR   KEGG; osa:4330968; -.
DR   eggNOG; KOG0107; Eukaryota.
DR   HOGENOM; CLU_012062_20_1_1; -.
DR   InParanoid; Q6K4N0; -.
DR   OMA; ASVWWEL; -.
DR   OrthoDB; 1533297at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000007752; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6K4N0; OS.
DR   GO; GO:0016607; C:nuclear speck; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   Pfam; PF00076; RRM_1; 1.
DR   Pfam; PF00098; zf-CCHC; 1.
DR   SMART; SM00360; RRM; 1.
DR   SMART; SM00343; ZnF_C2HC; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   SUPFAM; SSF57756; SSF57756; 1.
DR   PROSITE; PS50102; RRM; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Zinc; Zinc-finger.
FT   CHAIN           1..185
FT                   /note="Serine/arginine-rich splicing factor RSZ21"
FT                   /id="PRO_0000416994"
FT   DOMAIN          2..73
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   ZN_FING         86..103
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   REGION          104..185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..150
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   185 AA;  21023 MW;  2F827BBBF0B02DB3 CRC64;
     MARLYVGNLD PRVTSGELED EFRVFGVLRS VWVARKPPGF AFIDFDDKRD AEDALRDLDG
     KNGWRVELSR NSSSRGGRDR HGGSEMKCYE CGETGHFARE CRLRIGPGGL GSGKRRSRSR
     SRSRSPQYRK SPTYGRRSYS PRDRSPRRRS VSPVRGRSYS RSPRGRGGSP YADGRDGGRY
     RRSRS