RT04_ARATH
ID RT04_ARATH Reviewed; 362 AA.
AC Q31708; A7KNK1; F4INE3; O03980; Q8S8J0;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 25-MAY-2022, entry version 151.
DE RecName: Full=Ribosomal protein S4, mitochondrial;
GN Name=RPS4; OrderedLocusNames=AtMg00290 {ECO:0000312|Araport:ATMG00290};
GN and
GN OrderedLocusNames=At2g07734 {ECO:0000312|Araport:AT2G07734};
OS Arabidopsis thaliana (Mouse-ear cress).
OG Mitochondrion.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND RNA EDITING.
RC STRAIN=cv. Columbia;
RX PubMed=8737990; DOI=10.1515/bchm3.1996.377.4.251;
RA Lippok B., Brennicke A., Unseld M.;
RT "The rps4-gene is encoded upstream of the nad2-gene in Arabidopsis
RT mitochondria.";
RL Biol. Chem. Hoppe-Seyler 377:251-257(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. C24;
RX PubMed=8988169; DOI=10.1038/ng0197-57;
RA Unseld M., Marienfeld J.R., Brandt P., Brennicke A.;
RT "The mitochondrial genome of Arabidopsis thaliana contains 57 genes in
RT 366,924 nucleotides.";
RL Nat. Genet. 15:57-61(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND RNA EDITING.
RX PubMed=10611383; DOI=10.1073/pnas.96.26.15324;
RA Giege P., Brennicke A.;
RT "RNA editing in Arabidopsis mitochondria effects 441 C to U changes in
RT ORFs.";
RL Proc. Natl. Acad. Sci. U.S.A. 96:15324-15329(1999).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. C24, cv. Columbia, and cv. Landsberg erecta;
RX PubMed=21951689; DOI=10.1186/1741-7007-9-64;
RA Davila J.I., Arrieta-Montiel M.P., Wamboldt Y., Cao J., Hagmann J.,
RA Shedge V., Xu Y.Z., Weigel D., Mackenzie S.A.;
RT "Double-strand break repair processes drive evolution of the mitochondrial
RT genome in Arabidopsis.";
RL BMC Biol. 9:64-64(2011).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (AT2G07734).
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [6]
RP GENOME REANNOTATION (AT2G07734).
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [7]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 31-344, AND RNA EDITING.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta; TISSUE=Rosette leaf;
RX PubMed=17565941; DOI=10.1534/genetics.107.073585;
RA Bentolila S., Elliott L.E., Hanson M.R.;
RT "Genetic architecture of mitochondrial editing in Arabidopsis thaliana.";
RL Genetics 178:1693-1708(2008).
CC -!- SUBCELLULAR LOCATION: Mitochondrion.
CC -!- RNA EDITING: Modified_positions=30 {ECO:0000269|PubMed:10611383,
CC ECO:0000269|PubMed:17565941, ECO:0000269|PubMed:8737990}, 77
CC {ECO:0000269|PubMed:10611383, ECO:0000269|PubMed:17565941,
CC ECO:0000269|PubMed:8737990}, 79 {ECO:0000269|PubMed:10611383,
CC ECO:0000269|PubMed:17565941, ECO:0000269|PubMed:8737990}, 100
CC {ECO:0000269|PubMed:10611383, ECO:0000269|PubMed:17565941,
CC ECO:0000269|PubMed:8737990}, 103 {ECO:0000269|PubMed:10611383,
CC ECO:0000269|PubMed:17565941, ECO:0000269|PubMed:8737990}, 115
CC {ECO:0000269|PubMed:10611383, ECO:0000269|PubMed:17565941,
CC ECO:0000269|PubMed:8737990}, 126 {ECO:0000269|PubMed:10611383,
CC ECO:0000269|PubMed:17565941, ECO:0000269|PubMed:8737990}, 175
CC {ECO:0000269|PubMed:10611383, ECO:0000269|PubMed:17565941,
CC ECO:0000269|PubMed:8737990}, 319 {ECO:0000269|PubMed:10611383,
CC ECO:0000269|PubMed:17565941, ECO:0000269|PubMed:8737990}, 323
CC {ECO:0000269|PubMed:10611383, ECO:0000269|PubMed:17565941,
CC ECO:0000269|PubMed:8737990}, 331 {ECO:0000269|PubMed:10611383,
CC ECO:0000269|PubMed:17565941, ECO:0000269|PubMed:8737990}, 348
CC {ECO:0000269|PubMed:10611383, ECO:0000269|PubMed:17565941,
CC ECO:0000269|PubMed:8737990}, 351 {ECO:0000269|PubMed:10611383,
CC ECO:0000269|PubMed:17565941, ECO:0000269|PubMed:8737990}, 353
CC {ECO:0000269|PubMed:10611383, ECO:0000269|PubMed:17565941,
CC ECO:0000269|PubMed:8737990};
CC -!- MISCELLANEOUS: A stretch of 270 kb of the mitochondrial genome is
CC duplicated within the centromere of chromosome 2 resulting in the
CC duplication of the gene. The expression of this duplicated gene
CC (At2g07734) is not demonstrated. It is also probably not RNA edited and
CC therefore differs in all the positions known to be edited.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family.
CC {ECO:0000305}.
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DR EMBL; X96535; CAA65380.1; ALT_SEQ; Genomic_DNA.
DR EMBL; Y08501; CAA69772.3; ALT_SEQ; Genomic_DNA.
DR EMBL; JF729200; AEK01253.1; ALT_SEQ; Genomic_DNA.
DR EMBL; JF729201; AEK01283.1; ALT_SEQ; Genomic_DNA.
DR EMBL; JF729202; AEK01333.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC006225; AAM15172.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC06112.1; ALT_SEQ; Genomic_DNA.
DR EMBL; EF488944; ABS50656.1; -; mRNA.
DR EMBL; EF488945; ABS50657.1; -; mRNA.
DR PIR; S71904; S71904.
DR RefSeq; NP_085497.1; NC_001284.2.
DR RefSeq; NP_178806.1; NM_126764.2.
DR PDB; 6XYW; EM; 3.86 A; Bc=1-362.
DR PDBsum; 6XYW; -.
DR AlphaFoldDB; Q31708; -.
DR SMR; Q31708; -.
DR BioGRID; 14; 1.
DR BioGRID; 795; 1.
DR IntAct; Q31708; 2.
DR STRING; 3702.AT2G07734.1; -.
DR PaxDb; Q31708; -.
DR PeptideAtlas; Q31708; -.
DR PRIDE; Q31708; -.
DR GeneID; 815406; -.
DR KEGG; ath:AT2G07734; -.
DR Araport; AT2G07734; -.
DR Araport; ATMG00290; -.
DR eggNOG; ENOG502QVNI; Eukaryota.
DR HOGENOM; CLU_071763_0_0_1; -.
DR InParanoid; Q31708; -.
DR OrthoDB; 868631at2759; -.
DR PRO; PR:Q31708; -.
DR Proteomes; UP000006548; Chromosome 2.
DR Proteomes; UP000006548; Mitochondrion (cv. C24).
DR Genevisible; Q31708; AT.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0015935; C:small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0045903; P:positive regulation of translational fidelity; IBA:GO_Central.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; -; 1.
DR InterPro; IPR022801; Ribosomal_S4/S9.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR PANTHER; PTHR11831; PTHR11831; 1.
DR Pfam; PF01479; S4; 1.
DR SMART; SM00363; S4; 1.
DR PROSITE; PS50889; S4; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Mitochondrion; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; RNA editing; RNA-binding; rRNA-binding.
FT CHAIN 1..362
FT /note="Ribosomal protein S4, mitochondrial"
FT /id="PRO_0000132684"
FT DOMAIN 105..179
FT /note="S4 RNA-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00182"
SQ SEQUENCE 362 AA; 43390 MW; 20335D0CBD850963 CRC64;
MWLLKKLIQR DIDLSPLRFQ TCRLLSGNVW NRELTIIQRR ILRRLRNRKR SIKKRKIYPK
KYLTSYIQLQ TTRKLPFFYG DLPITEMHRG TKRTSYIPFL LNLETRFDVI PLRLYFLETI
PQARQLISHR RVCVNKGMVS ITHFKLSHGD IISFQENNAI IRGEEIRRSF YKEILVEKII
GKLLHQPLRM WRRSKTEWFH LLKTKRGCRL LLKSRFLQQL RSSMQEEDLE RTKKFGSEKV
CLGSSFAEHK RMKRNLLKSL FLSKRRKDKN LNLPTRTISP IVYNSSLSLY SNSTYCFASP
HKLTMKRRIK RIELPTHYLE VNYRTPKAVV FYGPNIGHIP HDIRLKDLNL LLWSRNGRGQ
NI
