RT06_BOVIN
ID RT06_BOVIN Reviewed; 124 AA.
AC P82931; Q3ZC18;
DT 04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 4.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=28S ribosomal protein S6, mitochondrial;
DE Short=MRP-S6;
DE Short=S6mt;
GN Name=MRPS6; Synonyms=RPMS6;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hypothalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 2-19, SUBCELLULAR LOCATION, AND SUBUNIT.
RX PubMed=11402041; DOI=10.1074/jbc.m103236200;
RA Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A.,
RA Watanabe K.;
RT "Proteomic analysis of the mammalian mitochondrial ribosome. Identification
RT of protein components in the 28S small subunit.";
RL J. Biol. Chem. 276:33181-33195(2001).
RN [3]
RP PROTEIN SEQUENCE OF 12-23 AND 104-116, SUBCELLULAR LOCATION, AND SUBUNIT.
RC TISSUE=Liver;
RX PubMed=11279123; DOI=10.1074/jbc.m100727200;
RA Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.;
RT "The small subunit of the mammalian mitochondrial ribosome: identification
RT of the full complement of ribosomal proteins present.";
RL J. Biol. Chem. 276:19363-19374(2001).
RN [4] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:11279123, ECO:0000269|PubMed:11402041,
CC ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11279123,
CC ECO:0000269|PubMed:11402041, ECO:0000269|PubMed:24799711}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS6 family.
CC {ECO:0000305}.
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DR EMBL; BC102978; AAI02979.1; -; mRNA.
DR RefSeq; NP_001035674.1; NM_001040584.2.
DR PDB; 3JD5; EM; 7.00 A; F=1-124.
DR PDB; 6NEQ; EM; 3.32 A; F=1-124.
DR PDB; 6NF8; EM; 3.48 A; F=1-124.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; P82931; -.
DR SMR; P82931; -.
DR CORUM; P82931; -.
DR IntAct; P82931; 2.
DR STRING; 9913.ENSBTAP00000016717; -.
DR PaxDb; P82931; -.
DR PRIDE; P82931; -.
DR Ensembl; ENSBTAT00000016717; ENSBTAP00000016717; ENSBTAG00000012594.
DR GeneID; 615431; -.
DR KEGG; bta:615431; -.
DR CTD; 64968; -.
DR VEuPathDB; HostDB:ENSBTAG00000012594; -.
DR VGNC; VGNC:31676; MRPS6.
DR eggNOG; KOG4708; Eukaryota.
DR GeneTree; ENSGT00390000014606; -.
DR InParanoid; P82931; -.
DR OMA; MTKHNQR; -.
DR OrthoDB; 1473530at2759; -.
DR Proteomes; UP000009136; Chromosome 1.
DR Bgee; ENSBTAG00000012594; Expressed in caput epididymis and 104 other tissues.
DR ExpressionAtlas; P82931; baseline and differential.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0070181; F:small ribosomal subunit rRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; HDA:UniProtKB.
DR GO; GO:0032543; P:mitochondrial translation; HDA:UniProtKB.
DR Gene3D; 3.30.70.60; -; 1.
DR InterPro; IPR000529; Ribosomal_S6.
DR InterPro; IPR035980; Ribosomal_S6_sf.
DR InterPro; IPR014717; Transl_elong_EF1B/ribosomal_S6.
DR PANTHER; PTHR21011; PTHR21011; 1.
DR Pfam; PF01250; Ribosomal_S6; 1.
DR SUPFAM; SSF54995; SSF54995; 1.
DR TIGRFAMs; TIGR00166; S6; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Mitochondrion; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:11402041"
FT CHAIN 2..124
FT /note="28S ribosomal protein S6, mitochondrial"
FT /id="PRO_0000176891"
FT STRAND 3..12
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 15..30
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 31..33
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 35..52
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 57..69
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 74..83
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 93..95
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 97..99
FT /evidence="ECO:0007829|PDB:6NEQ"
SQ SEQUENCE 124 AA; 14148 MW; A85114B7B8255657 CRC64;
MPRYELALIL KAMQRPETAA ALKRTLEALM DRGAVVRSLE NLGERTLPYK MSAHSQRHTR
GGYFLVDFYA PTTTVASIME HLSRDIDVIR PNVVKHPLTQ EVKECEGIVP VPLEEKLYST
KKRK
