RT09_BOVIN
ID RT09_BOVIN Reviewed; 396 AA.
AC Q58DQ5; P82676; Q0V8L9; Q32LH0; Q5BIN8;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 3.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=28S ribosomal protein S9, mitochondrial;
DE Short=MRP-S9;
DE Short=S9mt;
DE Flags: Precursor;
GN Name=MRPS9;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP PROTEIN SEQUENCE OF 77-83; 85-119; 135-151; 156-168; 203-212 AND 257-271,
RP SUBUNIT, AND SUBCELLULAR LOCATION.
RC TISSUE=Liver;
RX PubMed=11344316; DOI=10.1110/ps.35301;
RA Koc E.C., Burkhart W., Blackburn K., Koc H., Moseley A., Spremulli L.L.;
RT "Identification of four proteins from the small subunit of the mammalian
RT mitochondrial ribosome using a proteomics approach.";
RL Protein Sci. 10:471-481(2001).
RN [4] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:11344316, ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11344316,
CC ECO:0000269|PubMed:24799711}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=Q58DQ5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q58DQ5-2; Sequence=VSP_019341;
CC Name=3;
CC IsoId=Q58DQ5-3; Sequence=VSP_021750;
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS9 family.
CC {ECO:0000305}.
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DR EMBL; BT021186; AAX31368.1; -; mRNA.
DR EMBL; BT021542; AAX46389.1; -; mRNA.
DR EMBL; BT026199; ABG67038.1; -; mRNA.
DR EMBL; BC109583; AAI09584.1; -; mRNA.
DR RefSeq; NP_001030409.1; NM_001035332.1. [Q58DQ5-2]
DR RefSeq; XP_005212500.1; XM_005212443.3. [Q58DQ5-1]
DR PDB; 3JD5; EM; 7.00 A; I=1-396.
DR PDB; 6NEQ; EM; 3.32 A; I=1-396.
DR PDB; 6NF8; EM; 3.48 A; I=1-396.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; Q58DQ5; -.
DR SMR; Q58DQ5; -.
DR CORUM; Q58DQ5; -.
DR IntAct; Q58DQ5; 1.
DR STRING; 9913.ENSBTAP00000008093; -.
DR iPTMnet; Q58DQ5; -.
DR PaxDb; Q58DQ5; -.
DR PRIDE; Q58DQ5; -.
DR Ensembl; ENSBTAT00000008093; ENSBTAP00000008093; ENSBTAG00000006150. [Q58DQ5-1]
DR GeneID; 519302; -.
DR KEGG; bta:519302; -.
DR CTD; 64965; -.
DR VEuPathDB; HostDB:ENSBTAG00000006150; -.
DR eggNOG; KOG1697; Eukaryota.
DR GeneTree; ENSGT00390000011204; -.
DR HOGENOM; CLU_060546_1_0_1; -.
DR InParanoid; Q58DQ5; -.
DR OMA; IFPRQRA; -.
DR OrthoDB; 1430790at2759; -.
DR TreeFam; TF106154; -.
DR Proteomes; UP000009136; Chromosome 11.
DR Bgee; ENSBTAG00000006150; Expressed in triceps brachii and 106 other tissues.
DR ExpressionAtlas; Q58DQ5; baseline and differential.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0015935; C:small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR InterPro; IPR000754; Ribosomal_S9.
DR InterPro; IPR020574; Ribosomal_S9_CS.
DR PANTHER; PTHR21569; PTHR21569; 1.
DR Pfam; PF00380; Ribosomal_S9; 1.
DR SUPFAM; SSF54211; SSF54211; 1.
DR PROSITE; PS00360; RIBOSOMAL_S9; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Direct protein sequencing;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN ?..396
FT /note="28S ribosomal protein S9, mitochondrial"
FT /id="PRO_0000030654"
FT REGION 374..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..389
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 311..396
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000303|Ref.2"
FT /id="VSP_021750"
FT VAR_SEQ 367..396
FT /note="AGLLTTDPRVRERKKPGQEGARRKFTWKKR -> GTASLSFCEP (in
FT isoform 2)"
FT /evidence="ECO:0000303|PubMed:16305752"
FT /id="VSP_019341"
FT CONFLICT 58
FT /note="T -> K (in Ref. 1; AAX31368)"
FT /evidence="ECO:0000305"
FT HELIX 71..92
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 96..98
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 101..111
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 119..122
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 128..131
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 146..148
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 151..153
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 156..177
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 202..208
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 209..211
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 215..229
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 236..242
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 263..265
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 268..278
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 280..288
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 300..303
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 307..320
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 323..325
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 331..335
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 338..352
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 353..355
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 358..365
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 366..368
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 369..371
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 384..388
FT /evidence="ECO:0007829|PDB:6NEQ"
SQ SEQUENCE 396 AA; 45231 MW; 5A58358C19DED004 CRC64;
MAAPSVSCGA AVPYRLFLAG RVSFAREQGL WKAAASGLQT GTRCQILRLK HSPAVTTTKN
VAALRRESYT VDFIKKQIEE FNIGKRHLAN MMGEDPETFT QEDVDRAITY LFPSGLFEKR
ARPIMKHPEE IFPKQRAVQW GEDGRPFHFL FYTGKQSYYS LMHEAYGKVL HAEERQDQLR
AKGLFSEKSK SKDLIGSRWL IKEELEEMLV EKLSDQDYAQ FIRLLERLSA LPCDAAEEEF
VGRFRRTVTV QSKKHLIEPL QYDEQGMAFS TGQGKRKTAN AEAVVYGHGS GKIEINGVDY
LLYFPVTQDR EQLMFPFHFL DRLGKHDVTC TVSGGGRSSQ AGAIRLAMSR ALCSFITEDE
VEWMRQAGLL TTDPRVRERK KPGQEGARRK FTWKKR
