RT09_MOUSE
ID RT09_MOUSE Reviewed; 390 AA.
AC Q9D7N3; Q14AZ3; Q6IS29; Q80W17;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 3.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=28S ribosomal protein S9, mitochondrial;
DE Short=MRP-S9;
DE Short=S9mt;
DE Flags: Precursor;
GN Name=Mrps9;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Tongue;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain, and Limb;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Pancreas, Spleen, and
RC Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000250|UniProtKB:P82933}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P82933}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS9 family.
CC {ECO:0000305}.
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DR EMBL; AK009082; BAB26060.2; -; mRNA.
DR EMBL; BC051936; AAH51936.1; -; mRNA.
DR EMBL; BC069980; AAH69980.1; -; mRNA.
DR EMBL; BC116437; AAI16438.1; -; mRNA.
DR CCDS; CCDS14918.1; -.
DR RefSeq; NP_076003.3; NM_023514.4.
DR AlphaFoldDB; Q9D7N3; -.
DR SMR; Q9D7N3; -.
DR BioGRID; 213503; 4.
DR ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit.
DR STRING; 10090.ENSMUSP00000056855; -.
DR iPTMnet; Q9D7N3; -.
DR PhosphoSitePlus; Q9D7N3; -.
DR EPD; Q9D7N3; -.
DR MaxQB; Q9D7N3; -.
DR PaxDb; Q9D7N3; -.
DR PeptideAtlas; Q9D7N3; -.
DR PRIDE; Q9D7N3; -.
DR ProteomicsDB; 256796; -.
DR Antibodypedia; 32981; 186 antibodies from 28 providers.
DR DNASU; 69527; -.
DR Ensembl; ENSMUST00000057208; ENSMUSP00000056855; ENSMUSG00000060679.
DR GeneID; 69527; -.
DR KEGG; mmu:69527; -.
DR UCSC; uc007ava.2; mouse.
DR CTD; 64965; -.
DR MGI; MGI:1916777; Mrps9.
DR VEuPathDB; HostDB:ENSMUSG00000060679; -.
DR eggNOG; KOG1697; Eukaryota.
DR GeneTree; ENSGT00390000011204; -.
DR HOGENOM; CLU_060546_1_0_1; -.
DR InParanoid; Q9D7N3; -.
DR OMA; IFPRQRA; -.
DR OrthoDB; 1430790at2759; -.
DR PhylomeDB; Q9D7N3; -.
DR TreeFam; TF106154; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 69527; 18 hits in 72 CRISPR screens.
DR ChiTaRS; Mrps9; mouse.
DR PRO; PR:Q9D7N3; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q9D7N3; protein.
DR Bgee; ENSMUSG00000060679; Expressed in paneth cell and 251 other tissues.
DR ExpressionAtlas; Q9D7N3; baseline and differential.
DR Genevisible; Q9D7N3; MM.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0005730; C:nucleolus; ISO:MGI.
DR GO; GO:0015935; C:small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR Gene3D; 3.30.230.10; -; 1.
DR InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR InterPro; IPR000754; Ribosomal_S9.
DR InterPro; IPR020574; Ribosomal_S9_CS.
DR PANTHER; PTHR21569; PTHR21569; 1.
DR Pfam; PF00380; Ribosomal_S9; 1.
DR SUPFAM; SSF54211; SSF54211; 1.
DR PROSITE; PS00360; RIBOSOMAL_S9; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN ?..390
FT /note="28S ribosomal protein S9, mitochondrial"
FT /id="PRO_0000030656"
FT REGION 368..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..383
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 14
FT /note="L -> P (in Ref. 1; BAB26060)"
FT /evidence="ECO:0000305"
FT CONFLICT 206
FT /note="K -> T (in Ref. 1; BAB26060)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 390 AA; 44929 MW; 50137A5251B98173 CRC64;
MAAPCVSCGR VLSLWFTPAV RASLCQRPGY WTASAVGWQT GTRFQLSKLI HTTVVTTKKN
VQASRQESYT EDFIKKQIEE FNIGKRHLAN MMGEDPETFA EEDIDRAIAY LFPSGLFEKR
ARPMMKHPEH IFPKQRATQW GEDGRPFHFL FYTGKQSYYS LMHDVYGKVM QLEKHRGPLS
ASAESRDLIG SRWLIKEELE EMLVEKLSDE DYAQFIRLLE KLLTLPCGPA EEEFVQRFRR
SVTIQSKKQL IEPVQYDEQG MAFSTSEGRR KSATAQAVVY EHGSGKIHVN GVDYLIYFPI
TQDREQLMFP FHFLDRLERH DVTCTVSGGG RSAQAGAIRL AMARALCSFV TEDEVEWMRQ
AGLLTPDPRI RERKKPGQEG ARRKFTWKKR
