RT106_ASPTN
ID RT106_ASPTN Reviewed; 468 AA.
AC Q0CTS1;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Histone chaperone rtt106;
GN Name=rtt106; ORFNames=ATEG_02913;
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156;
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Histones H3 and H4 chaperone involved in the nucleosome
CC formation and heterochromatin silencing. Required for the deposition of
CC H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role
CC in the transcriptional regulation of the cell-cycle dependent histone
CC genes by creating a repressive structure at the core histone gene
CC promoter (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with histones H3 and H4. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RTT106 family. {ECO:0000305}.
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DR EMBL; CH476597; EAU36187.1; -; Genomic_DNA.
DR RefSeq; XP_001212091.1; XM_001212091.1.
DR AlphaFoldDB; Q0CTS1; -.
DR SMR; Q0CTS1; -.
DR STRING; 341663.Q0CTS1; -.
DR EnsemblFungi; EAU36187; EAU36187; ATEG_02913.
DR GeneID; 4317477; -.
DR VEuPathDB; FungiDB:ATEG_02913; -.
DR eggNOG; ENOG502R9PE; Eukaryota.
DR HOGENOM; CLU_033828_0_0_1; -.
DR OMA; AMPEAHR; -.
DR OrthoDB; 1283058at2759; -.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR013719; DUF1747.
DR InterPro; IPR011993; PH-like_dom_sf.
DR Pfam; PF08512; Rtt106; 1.
DR SMART; SM01287; Rtt106; 1.
PE 3: Inferred from homology;
KW Chaperone; Chromosome; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..468
FT /note="Histone chaperone rtt106"
FT /id="PRO_0000320486"
FT REGION 67..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 368..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..451
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 50696 MW; 47C2A4192EABD774 CRC64;
MAFATINSSA IPPATPSSIP TIEHAFASEP SLRKRVYDAI GATPQYIPLF EDIARYTSSL
LARNATSTAP PAEASADGPA AKKRKIQNGD VSGTPQSLGD LKADAELQFH MRDVSFAMPQ
RKKLTLEVTA GGGFLRARNQ TSKEVEFGVP VEKIQHVLCL PVPEKNQRQF NFCVIPQNGD
GINTPAGGEA APESIVWTVA DGPPKSEFSI NGQAVAGGAG GESAEKVVLR VLNDALTQTK
VIRPDDREFV SAMPEAHRKG EKAYHVKAFR GSKEGYLFFL STGILFGFKK PLIFFAFENI
DSVSYTSVLQ RTFNLNIMAR ATAGGEPQEF ELSMIDQADF SGIDAYIKTH GLQDASLAEE
RRAKRYNING KTEEAAAAAN GDETAEEESE LQKAQRELED QEDEEEEDYD PGSDGDSDGS
GSSSDDDDDD DDEHQDDEDD MDEDEDGEQD LVAAELGSQA ADIPEDQV
